BGC0002362: loseolamycin A1 biosynthetic gene cluster from Micromonospora endolithica
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Location: 1 - 24,294 nt. (total: 24,294 nt).
This entry is originally from NCBI GenBank MT904273.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002362
Short description loseolamycin A1 biosynthetic gene cluster from Micromonospora endolithica
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MT904273.1
1 - 24294
via Heterologous expression, Gene expression correlated with compound production
Compounds
  • loseolamycin A1
  • loseolamycin A2
Species Micromonospora endolithica [taxonomy]
References
Chemical products information
loseolamycin A1 Evidence:
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Chemical database entries
NPAtlas
loseolamycin A2 Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QZS07520.1
 2 - 1300 (+) hypothetical protein
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    • QZS07497.1
    		 1297 - 2193 (+) hypothetical protein
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      • QZS07498.1
      		 2288 - 3046 (+) hypothetical protein
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        • QZS07499.1
        		 3050 - 3790 (-) hypothetical protein
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          • QZS07500.1
          		 3878 - 4618 (-) hypothetical protein
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            • QZS07501.1
            		 4710 - 6218 (+) hypothetical protein
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              • QZS07502.1
              		 6331 - 6681 (+) hypothetical protein
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                • QZS07503.1
                		 7166 - 9703 (+) hypothetical protein
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                  • QZS07504.1
                  		 9793 - 10698 (-) hypothetical protein
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                    • QZS07505.1
                    		 10795 - 11307 (+) hypothetical protein
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                      • QZS07506.1
                      		 11304 - 11867 (+) hypothetical protein
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                        • QZS07507.1
                        		 11985 - 12746 (+) hypothetical protein
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                          • QZS07508.1
                          		 12753 - 13943 (-) hypothetical protein
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                            • QZS07509.1
                            		 14080 - 15528 (-) hypothetical protein
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                              • QZS07510.1
                              		 15636 - 16418 (-) hypothetical protein
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                                • QZS07511.1
                                		 16559 - 17392 (-) hypothetical protein
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                                  • QZS07512.1
                                  		 17444 - 18199 (+) hypothetical protein
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                                    • QZS07513.1
                                    		 18243 - 19409 (+) hypothetical protein
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                                      • QZS07521.1
                                      • losA
                                      		 19551 - 20600 (+) type III polyketide synthase
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                                        • QZS07514.1
                                        		 20641 - 21204 (+) hypothetical protein
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                                          • QZS07515.1
                                          		 21212 - 21907 (-) hypothetical protein
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                                            • QZS07516.1
                                            		 22241 - 22726 (+) hypothetical protein
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                                              • QZS07517.1
                                              		 22780 - 23475 (+) hypothetical protein
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                                                • QZS07518.1
                                                		 23492 - 23974 (+) hypothetical protein
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                                                  • QZS07519.1
                                                  		 24017 - >24294 (+) hypothetical protein
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                                                    Biosynthesis information
                                                    Annotation changelog

                                                    Entry version: 2

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-10-07
                                                    Update chemical activity to schema version 2.11
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-10-07
                                                    Added chemical structures for compounds: loseolamycin A1, loseolamycin A2.
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-10-07
                                                    Added NPAtlas links to compounds: loseolamycin A1, loseolamycin A2.
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-09-15
                                                    Entry added
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-09-15
                                                    Updated bioactivity data
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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