BGC0002426: deschlorosvetamycin A biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 52,935 nt. (total: 52,935 nt).
This entry is originally from NCBI GenBank MW810086.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002426
Short description deschlorosvetamycin A biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MW810086.1
via
Compounds
  • deschlorosvetamycin A
  • svetamycin H
  • svetamycin A
Species Streptomyces sp. [taxonomy]
References
Chemical products information
deschlorosvetamycin A Evidence:
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Chemical database entries
NPAtlas
svetamycin H Evidence:
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Chemical database entries
NPAtlas
svetamycin A Evidence:
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Chemical database entries
NPAtlas
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QXL90809.1
 126 - 935 (+) hypothetical protein
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    • QXL90810.1
    		 932 - 1999 (+) hypothetical protein
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      • QXL90811.1
      		 2155 - 3336 (+) hypothetical protein
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        • QXL90812.1
        		 3382 - 4137 (+) L,D-transpeptidase
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          • QXL90813.1
          • babR1
          		 4334 - 5893 (+) sigma-70 family RNA polymerase sigma factor
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            • QXL90814.1
            • babR2
            		 5921 - 6991 (-) AsnC family transcriptional regulator
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              • QXL90815.1
              • babT1
              		 7176 - 8567 (+) MFS transporter
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                • QXL90816.1
                • babA
                		 8564 - 9775 (+) amidohydrolase
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                  • QXL90817.1
                  • babR3
                  		 9795 - 10580 (+) DeoR/GlpR transcriptional regulator
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                    • QXL90818.1
                    • babB
                    		 10614 - 10991 (+) hypothetical protein
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                      • QXL90819.1
                      • babC
                      		 10988 - 11656 (+) NUDIX domain-containing protein
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                        • QXL90820.1
                        • babD
                        		 11683 - 12561 (+) NAD(P)-dependent oxidoreductase
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                          • QXL90821.1
                          • babO1
                          		 12583 - 13800 (-) cytochrome P450
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                            • QXL90822.1
                            • babO2
                            		 13854 - 15473 (-) FAD-binding monooxygenase
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                              • QXL90823.1
                              • babM1
                              		 15791 - 16525 (+) methyltransferase
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                                • QXL90824.1
                                • babO3
                                		 16555 - 18186 (-) FAD-dependent monooxygenase
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                                  • QXL90825.1
                                  • babM2
                                  		 18186 - 18932 (-) methyltransferase
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                                    • QXL90826.1
                                    • babR4
                                    		 19489 - 20079 (-) TetR family transcriptional regulator
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                                      • QXL90827.1
                                      • babT2
                                      		 20160 - 21752 (+) MFS transporter
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                                        • QXL90828.1
                                        • babE
                                        		 22192 - 22932 (+) glyoxalase
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                                          • QXL90829.1
                                          • babM3
                                          		 23004 - 24038 (-) O-methyltransferase
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                                            • QXL90830.1
                                            • babF
                                            		 24103 - 24801 (-) 3-oxoacyl-(acyl-carrier protein) reductase
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                                              • QXL90831.1
                                              • babT3
                                              		 24785 - 26122 (-) potassium transporter
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                                                • QXL90832.1
                                                • babH1
                                                		 26122 - 27399 (-) halogenase
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                                                  • QXL90833.1
                                                  • babG
                                                  		 27443 - 27799 (-) cyclase
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                                                    • QXL90834.1
                                                    • babI
                                                    		 27796 - 28287 (-) polyketide cyclase
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                                                      • QXL90835.1
                                                      • babJ
                                                      		 28284 - 28523 (-) putative acyl carrier protein
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                                                        • QXL90836.1
                                                        • babK
                                                        		 28560 - 29819 (-) keto-acyl synthase beta
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                                                          • QXL90837.1
                                                          • babL
                                                          		 29816 - 31081 (-) polyketide beta-ketoacyl synthase alpha
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                                                            • QXL90838.1
                                                            • babN
                                                            		 31078 - 31479 (-) polyketide WhiE II
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                                                              • QXL90839.1
                                                              • babP
                                                              		 31476 - 32153 (-) WhiE protein
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                                                                • QXL90840.1
                                                                • babT4
                                                                		 32272 - 33747 (-) MFS transporter
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                                                                  • QXL90841.1
                                                                  • babR5
                                                                  		 33862 - 34527 (+) transcriptional regulator TetR family
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                                                                    • QXL90842.1
                                                                    • babM4
                                                                    		 34490 - 35545 (+) methyltransferase
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                                                                      • QXL90843.1
                                                                      • babR6
                                                                      		 35571 - 38414 (-) LuxR family transcriptional regulator
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                                                                        • QXL90844.1
                                                                        • babR7
                                                                        		 38571 - 40472 (-) AfsR/SARP family transcriptional regulator
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                                                                          • QXL90845.1
                                                                          • babO4
                                                                          		 40623 - 41891 (-) RebP-like cytochrome P450
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                                                                            • QXL90846.1
                                                                            • babQ
                                                                            		 41916 - 45134 (-) chromopyrolic acid synthase
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                                                                              • QXL90847.1
                                                                              • babS
                                                                              		 45131 - 46594 (-) FAD-dependent oxidoreductase
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                                                                                • QXL90848.1
                                                                                • babH2
                                                                                		 46837 - 48426 (+) BabH2 tryptophan 7-halogenase
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                                                                                  • QXL90849.1
                                                                                  • babU
                                                                                  		 48423 - 48950 (+) flavin reductase family protein
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                                                                                    • QXL90850.1
                                                                                    • babV
                                                                                    		 48956 - 49639 (-) alpha/beta hydrolase
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                                                                                      • QXL90851.1
                                                                                      • babW
                                                                                      		 49636 - 50124 (-) SnoaL-like domain-containing protein
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                                                                                        • QXL90852.1
                                                                                        • babX
                                                                                        		 50186 - 51133 (-) zinc-binding dehydrogenase
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                                                                                          • QXL90853.1
                                                                                          • babR8
                                                                                          		 51269 - 51901 (-) TetR family transcriptional regulator
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                                                                                            • QXL90854.1
                                                                                            		 52200 - 52559 (+) hypothetical protein
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                                                                                              • QXL90855.1
                                                                                              		 52594 - 52812 (+) hypothetical protein
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                                                                                                Biosynthesis information
                                                                                                Annotation changelog

                                                                                                Entry version: 2

                                                                                                Date
                                                                                                Changes
                                                                                                Submitters
                                                                                                Reviewers
                                                                                                2022-10-07
                                                                                                Added chemical structures for compounds: deschlorosvetamycin A, svetamycin H.
                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                2022-10-07
                                                                                                Added NPAtlas links to compounds: deschlorosvetamycin A, svetamycin H.
                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                Entry version: 1

                                                                                                Date
                                                                                                Changes
                                                                                                Submitters
                                                                                                Reviewers
                                                                                                2022-09-15
                                                                                                Entry added
                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                Detailed domain annotation
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