BGC0002456: alchivemycin A biosynthetic gene cluster from Streptomyces sp. NBRC 109436
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Location: 1 - 120,445 nt. (total: 120,445 nt).
This entry is originally from NCBI GenBank MW490597.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
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Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002456
Short description alchivemycin A biosynthetic gene cluster from Streptomyces sp. NBRC 109436
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
  • NRPS (Type I)
Loci
MW490597.1
1 - 120445
via Knock-out studies, Enzymatic assays
Compounds
  • alchivemycin A
  • alchivemycin B
Species Streptomyces sp. NBRC 109436 [taxonomy]
References
Chemical products information
alchivemycin A Evidence:
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Chemical database entries
NPAtlas
alchivemycin B Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QSV12658.1
 4543 - 4932 (+) AvmS4
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    • QSV12653.1
    		 5521 - 9003 (+) AvmK
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      • QSV12654.1
      		 9104 - 13003 (+) AvmL
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        • QSV12647.1
        		 13198 - 14778 (-) AvmO1
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          • QSV12648.1
          		 15092 - 16624 (+) AvmO2
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            • QSV12656.1
            		 18407 - 21760 (+) AvmN
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              • QSV12651.1
              		 21841 - 23055 (+) AvmP
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                • QSV12652.1
                		 23187 - 24068 (-) AvmR
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                  • QSV12655.1
                  		 24313 - 33636 (+) AvmA
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                    • QSV12659.1
                    		 33681 - 42353 (+) AvmB
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                      • QSV12661.1
                      		 42404 - 53599 (+) AvmC
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                        • QSV12662.1
                        		 53936 - 76900 (+) AvmD
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                          • QSV12663.1
                          		 77161 - 90225 (+) AvmE
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                            • QSV12664.1
                            		 90251 - 101164 (+) AvmF
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                              • QSV12650.1
                              		 101439 - 102362 (-) AvmO4
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                                • QSV12649.1
                                		 102599 - 104203 (+) AvmO3
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                                  • QSV12657.1
                                  		 104734 - 105984 (+) AvmX
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                                    • QSV12660.1
                                    		 106081 - 106680 (+) AvmT
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                                      Biosynthesis information

                                      No biosynthesis information available for this record.

                                      Annotation changelog

                                      Entry version: 2

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-10-07
                                      Update chemical activity to schema version 2.11
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 1

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-09-15
                                      Entry added
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2022-09-15
                                      Updated bioactivity data
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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