BGC0002517: tripartilactam biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 73,855 nt. (total: 73,855 nt).
This entry is originally from NCBI GenBank MN305323.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002517
Short description tripartilactam biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MN305323.1
1 - 73855
via Knock-out studies
Compounds
  • tripartilactam
  • niizalactam C
Species Streptomyces sp. [taxonomy]
References
Chemical products information
tripartilactam Evidence:
(no structure information available)
niizalactam C Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QGA70077.1
  • triB
 1 - 2790 (+) LuxR family transcriptional regulator
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    • QGA70078.1
    • triA2
    		 2872 - 13383 (-) type I polyketide synthase
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      • QGA70079.1
      • triA1
      		 13493 - 24241 (-) type I polyketide synthase
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        • QGA70080.1
        • triC
        		 24324 - 25613 (-) glutamate mutase E-chain
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          • QGA70081.1
          • triD
          		 25610 - 26062 (-) glutamate mutase S-chain
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            • QGA70082.1
            • triE
            		 26062 - 27300 (-) decarboxylase
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              • QGA70083.1
              • triF
              		 27297 - 28823 (-) ATP-dependent ligase
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                • QGA70084.1
                • triG
                		 28820 - 30382 (-) ATP-dependent ligase
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                  • QGA70085.1
                  • triH
                  		 30408 - 30659 (-) acyl carrier protein
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                    • QGA70086.1
                    • triI
                    		 30686 - 31621 (-) acyl transferase
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                      • QGA70087.1
                      • triJ
                      		 31735 - 32631 (-) peptidase
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                        • QGA70088.1
                        • triK
                        		 33718 - 34950 (+) cytochrome P450
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                          • QGA70089.1
                          • triL
                          		 35009 - 36244 (+) cytochrome P450
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                            • QGA70090.1
                            • triM
                            		 36271 - 36462 (+) ferredoxin
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                              • QGA70091.1
                              • triN
                              		 36545 - 37408 (-) putative oxidoreductase
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                                • QGA70092.1
                                • triO
                                		 37405 - 38160 (-) thioesterase
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                                  • QGA70093.1
                                  • triP
                                  		 38271 - 38915 (-) LuxR family transcriptional regulator
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                                    • QGA70094.1
                                    • triQ
                                    		 38879 - 40210 (-) histidine kinase
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                                      • QGA70095.1
                                      • triR
                                      		 40264 - 42774 (-) ABC transporter permease
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                                        • QGA70096.1
                                        • triS
                                        		 42774 - 43577 (-) ABC transporter
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                                          • QGA70097.1
                                          • triT
                                          		 43865 - 44119 (+) hypothetical protein
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                                            • QGA70098.1
                                            • triA6
                                            		 44186 - 48040 (-) type I polyketide synthase
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                                              • QGA70099.1
                                              • triA5
                                              		 48134 - 63535 (-) type I polyketide synthase
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                                                • QGA70100.1
                                                • triA4
                                                		 63603 - 68351 (-) type I polyketide synthase
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                                                  • QGA70101.1
                                                  • triA3
                                                  		 68351 - 73855 (-) type I polyketide synthase
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                                                    Biosynthesis information
                                                    Annotation changelog

                                                    Entry version: 2

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-10-07
                                                    Update chemical activity to schema version 2.11
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-09-15
                                                    Entry added
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-09-15
                                                    Updated bioactivity data
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    Detailed domain annotation
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