BGC0002540: tetramycin B biosynthetic gene cluster from Streptomyces hygrospinosus subsp. beijingensis
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Location: 1 - 108,563 nt. (total: 108,563 nt).
This entry is originally from NCBI GenBank MN604040.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002540
Short description tetramycin B biosynthetic gene cluster from Streptomyces hygrospinosus subsp. beijingensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MN604040.1
1 - 108563
via Heterologous expression
Compounds
  • tetramycin B
Species Streptomyces hygrospinosus subsp. beijingensis [taxonomy]
References
Chemical products information
tetramycin B Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QIZ24090.1
  • tetrJ
 2645 - 3994 (-) putative crotonyl-CoA reductase
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    • QIZ24091.1
    • tetrTI
    		 4037 - 5845 (-) putative ABC transporter
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      • QIZ24092.1
      • tetrTII
      		 5823 - 7808 (-) putative ABC transporter
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        • QIZ24093.1
        • tetrMI
        		 8007 - 9035 (+) putative mycosamine dehydratase
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          • QIZ24094.1
          • tetrRI
          		 9435 - 12329 (+) transcriptional regulator
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            • QIZ24095.1
            • tetrRII
            		 12355 - 15138 (+) transcriptional regulator
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              • QIZ24096.1
              • tetrRIII
              		 15187 - 17850 (+) LAL transcriptional regulator
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                • QIZ24097.1
                • tetrRIV
                		 18281 - 18904 (+) positive regulator
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                  • QIZ24098.1
                  • tetrC
                  		 19256 - 47746 (+) type I polyketide synthase
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                    • QIZ24099.1
                    • tetrD
                    		 47758 - 53139 (+) type I polyketide synthase
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                      • QIZ24100.1
                      • tetrE
                      		 53174 - 60202 (+) type I polyketide synthase
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                        • QIZ24101.1
                        • tetrK
                        		 60268 - 61458 (-) cytochrome P450 monooxygenase
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                          • QIZ24102.1
                          • tetrB
                          		 61714 - 82071 (+) type I polyketide synthase
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                            • QIZ24103.1
                            • tetrL
                            		 82682 - 83803 (-) tyrosine phosphatase
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                              • QIZ24104.1
                              • tetrA
                              		 84035 - 89242 (-) type I polyketide synthase
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                                • QIZ24105.1
                                • tetrF
                                		 89313 - 89504 (-) ferredoxin
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                                  • QIZ24106.1
                                  • tetrG
                                  		 89597 - 90772 (-) cytochrome P450 monooxygenase
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                                    • QIZ24107.1
                                    • tetrMII
                                    		 90804 - 91862 (-) aminotransferase
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                                      • QIZ24108.1
                                      • tetrMIII
                                      		 91919 - 93307 (-) putative glucosyl transferase
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                                        • QIZ24109.1
                                        • tetrO
                                        		 93524 - 95185 (-) cholesterol oxidase
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                                          Biosynthesis information

                                          No biosynthesis information available for this record.

                                          Annotation changelog

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2024-07-24
                                          MIBiG v4 annotathon
                                          • (ID: C62OJVVH7XOTOTFZSJT727YU)
                                          • (ID: X3QVFXOIMTNXSB4JQGP4RI6A)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Added chemical structures for compounds: tetramycin B.
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-10-07
                                          Added NPAtlas links to compounds: tetramycin B.
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Entry added
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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