BGC0002716: gamexpeptide A biosynthetic gene cluster from Photorhabdus laumondii subsp. laumondii
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Location: 3,846,999 - 3,900,195 nt. (total: 53,197 nt).
This entry is originally from NCBI GenBank CP024901.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002716
Short description gamexpeptide A biosynthetic gene cluster from Photorhabdus laumondii subsp. laumondii
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP024901.1
3846999 - 3900195
via Heterologous expression
Compounds
  • gamexpeptide A
  • gamexpeptide B
  • gamexpeptide E
  • luminmide B
  • luminmide D
  • luminmide E
  • luminmide F
  • luminmide G
Species Photorhabdus laumondii subsp. laumondii [taxonomy]
References
Chemical products information
gamexpeptide A Evidence:
(no structure information available)
gamexpeptide B Evidence:
(no structure information available)
gamexpeptide E Evidence:
(no structure information available)
luminmide B Evidence:
(no structure information available)
luminmide D Evidence:
(no structure information available)
luminmide E Evidence:
(no structure information available)
luminmide F Evidence:
(no structure information available)
luminmide G Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • PluTT01m_16730
  • AXG49888.1
 3846999 - 3848078 (-) hypothetical protein
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    • PluTT01m_16735
    • AXG48259.1
    		 3848098 - 3848319 (-) hypothetical protein
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      • PluTT01m_16740
      • AXG48260.1
      		 3848338 - 3848571 (-) hypothetical protein
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        • PluTT01m_16745
        • AXG48261.1
        		 3848659 - 3849765 (-) hypothetical protein
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          • PluTT01m_16750
          • AXG48262.1
          		 3849887 - 3850978 (-) hypothetical protein
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            • PluTT01m_16755
            • AXG48263.1
            		 3850971 - 3852581 (-) hypothetical protein
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              • PluTT01m_16760
              • AXG48264.1
              		 3852584 - 3855112 (-) type VI secretion system tip protein VgrG
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                • PluTT01m_16765
                • AXG48265.1
                		 3855289 - 3855780 (-) type VI secretion system tube protein Hcp
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                  • PluTT01m_16770
                  • AXG48266.1
                  		 3855799 - 3857526 (-) hypothetical protein
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                    • PluTT01m_16775
                    • AXG48267.1
                    		 3857523 - 3857810 (-) hypothetical protein
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                      • PluTT01m_16780
                      • AXG48268.1
                      		 3857839 - 3858204 (+) IS66 family insertion sequence hypothetical protein
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                        • PluTT01m_16785
                        • AXG48269.1
                        		 3858198 - 3858533 (+) IS66 family insertion sequence hypothetical protein
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                          • PluTT01m_16790
                          • AXG48270.1
                          		 3858597 - 3860102 (+) IS66 family transposase ISPlu20
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                            • PluTT01m_16795
                            • AXG48271.1
                            		 3860152 - 3860544 (-) hypothetical protein
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                              • PluTT01m_16800
                              • AXG48272.1
                              		 3860541 - 3861890 (-) type VI secretion system baseplate subunit TssK
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                                • PluTT01m_16805
                                • AXG48273.1
                                		 3861906 - 3863432 (-) type VI secretion system contractile sheath large subunit
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                                  • PluTT01m_16810
                                  • AXG48274.1
                                  		 3863464 - 3863961 (-) type VI secretion system contractile sheath small subunit
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                                    • PluTT01m_16815
                                    • AXG48275.1
                                    		 3865117 - 3880767 (-) non-ribosomal peptide synthetase
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                                      • PluTT01m_16820
                                      		 3881942 - 3882916 (-) serine 3-dehydrogenase
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                                        • PluTT01m_16825
                                        • AXG48276.1
                                        		 3882973 - 3883998 (+) IS630 family transposase ISPlu19
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                                          • PluTT01m_16830
                                          		 3884013 - 3884483 (-) serine 3-dehydrogenase
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                                            • PluTT01m_16835
                                            • AXG48277.1
                                            		 3884599 - 3886215 (-) IS1634 family transposase ISPlu4
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                                              • PluTT01m_16840
                                              • AXG48278.1
                                              		 3886583 - 3887596 (-) IS630 family transposase ISPlu10
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                                                • PluTT01m_16845
                                                		 3888670 - 3889631 (+) hypothetical protein
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                                                  • PluTT01m_16850
                                                  • AXG48279.1
                                                  		 3889615 - 3889866 (+) hypothetical protein
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                                                    • PluTT01m_16855
                                                    • AXG48280.1
                                                    		 3889853 - 3891649 (+) DUF2326 domain-containing protein
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                                                      • PluTT01m_16860
                                                      • AXG48281.1
                                                      		 3891741 - 3892163 (-) enhanced serine sensitivity protein SseB
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                                                        • PluTT01m_16865
                                                        • AXG48282.1
                                                        		 3892199 - 3893494 (-) peptidase B
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                                                          • PluTT01m_16870
                                                          • AXG48283.1
                                                          		 3893803 - 3894003 (-) Fe-S assembly protein IscX
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                                                            • PluTT01m_16875
                                                            • AXG48284.1
                                                            • fdx
                                                            		 3894022 - 3894357 (-) ISC system 2Fe-2S type ferredoxin
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                                                              • PluTT01m_16880
                                                              • AXG48285.1
                                                              • hscA
                                                              		 3894360 - 3896210 (-) molecular chaperone HscA
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                                                                • PluTT01m_16885
                                                                • AXG48286.1
                                                                • hscB
                                                                		 3896222 - 3896743 (-) co-chaperone protein HscB
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                                                                  • PluTT01m_16890
                                                                  • AXG48287.1
                                                                  		 3896781 - 3897104 (-) iron-sulfur cluster assembly accessory protein
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                                                                    • PluTT01m_16895
                                                                    • AXG48288.1
                                                                    		 3897214 - 3897600 (-) Fe-S cluster assembly scaffold IscU
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                                                                      • PluTT01m_16900
                                                                      • AXG48289.1
                                                                      		 3897625 - 3898839 (-) IscS subfamily cysteine desulfurase
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                                                                        • PluTT01m_16905
                                                                        • AXG48290.1
                                                                        		 3898889 - 3899383 (-) Fe-S cluster assembly transcriptional regulator IscR
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                                                                          • PluTT01m_16910
                                                                          • AXG48291.1
                                                                          		 3899470 - 3900195 (-) tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ
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                                                                            Biosynthesis information

                                                                            Biosynthetic modules

                                                                            Name
                                                                            Unk01
                                                                            Type
                                                                            nrps-type1
                                                                            Genes
                                                                            PluTT01m_16815
                                                                            Substrates
                                                                            valine, isoleucine (evidence: Structure-based inference [1])
                                                                            Integrated Monomers
                                                                            Domains
                                                                            adenylation
                                                                            Name
                                                                            Unk02
                                                                            Type
                                                                            nrps-type1
                                                                            Genes
                                                                            PluTT01m_16815
                                                                            Substrates
                                                                            leucine (evidence: Structure-based inference [1])
                                                                            Integrated Monomers
                                                                            Domains
                                                                            adenylation
                                                                            Name
                                                                            Unk03
                                                                            Type
                                                                            nrps-type1
                                                                            Genes
                                                                            PluTT01m_16815
                                                                            Substrates
                                                                            phenylalanine, leucine, tyrosine, methionine, valine, 4-aminophenylalanine (evidence: Structure-based inference [1])
                                                                            Integrated Monomers
                                                                            Domains
                                                                            adenylation
                                                                            Name
                                                                            Unk04
                                                                            Type
                                                                            nrps-type1
                                                                            Genes
                                                                            PluTT01m_16815
                                                                            Substrates
                                                                            leucine (evidence: Structure-based inference [1])
                                                                            Integrated Monomers
                                                                            Domains
                                                                            adenylation
                                                                            Name
                                                                            Unk05
                                                                            Type
                                                                            nrps-type1
                                                                            Genes
                                                                            PluTT01m_16815
                                                                            Substrates
                                                                            leucine (evidence: Structure-based inference [1])
                                                                            Integrated Monomers
                                                                            Domains
                                                                            adenylation
                                                                            Annotation changelog

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-09-15
                                                                            Entry added
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2022-09-15
                                                                            Added NRP substrate specificities
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            Detailed domain annotation
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