BGC0000128 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000128 (Pseudomonas sp. M18)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	32,800	pyoluteorin	Polyketide	94%

BGC0000128 - Region 1 - T1PKS

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Location: 1 - 32,800 nt. (total: 32,800 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 32,801
Label		BGC0000128

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000128.1	0.83	Polyketide	pyoluteorin	Pseudomonas sp. M18
BGC0000127.1	0.45	Polyketide	pyoluteorin	Pseudomonas protegens Pf-5
BGC0001778.1	0.31	Other	showdomycin	Streptomyces showdoensis
BGC0001160.1	0.31	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0001163.1	0.30	Polyketide	1-heptadecene	Moorea producens 3L
BGC0000924.1	0.29	Other	pyrrolnitrin	Pseudomonas chlororaphis
BGC0001161.1	0.29	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0000003.1	0.28	Polyketide	AF-toxin	Alternaria alternata
BGC0001405.1	0.27	Polyketide	chaetoviridin E, 11-epichaetomugilin A	Chaetomium globosum CBS 148.51
BGC0000046.1	0.26	Polyketide	depudecin	Alternaria brassicicola

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000128.1	0.94	Polyketide	pyoluteorin	Pseudomonas sp. M18
BGC0000127.1	0.76	Polyketide	pyoluteorin	Pseudomonas protegens Pf-5
BGC0001778.1	0.64	Other	showdomycin	Streptomyces showdoensis
BGC0001160.1	0.64	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0001163.1	0.63	Polyketide	1-heptadecene	Moorea producens 3L
BGC0000924.1	0.62	Other	pyrrolnitrin	Pseudomonas chlororaphis
BGC0001161.1	0.62	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0000003.1	0.62	Polyketide	AF-toxin	Alternaria alternata
BGC0001405.1	0.61	Polyketide	chaetoviridin E, 11-epichaetomugilin A	Chaetomium globosum CBS 148.51
BGC0000046.1	0.60	Polyketide	depudecin	Alternaria brassicicola

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 32800:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (mal) + (ohmal)
Non-colinear ordering:: pltB + pltC

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

pltB

PKS_AT (534..826): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; 2-Methylbutyryl-CoA: 66.7%; Methylmalonyl-CoA: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 121.7
Methylmalonyl-CoA: 104.7
Methoxymalonyl-CoA: 87.9
Isobutyryl-CoA: 71.3
2-Methylbutyryl-CoA: 66.7
Ethylmalonyl-CoA: 63.1
Propionyl-CoA: 55.0
CHC-CoA: 46.0
fatty_acid: 44.4
trans-1,2-CPDA: 39.0
inactive: 36.2
Benzoyl-CoA: 30.9
Acetyl-CoA: 25.9
3-Methylbutyryl-CoA: 14.5

pltC

PKS_AT (570..868): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Propionyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 176.6
inactive: 100.1
Methylmalonyl-CoA: 65.1
Methoxymalonyl-CoA: 63.7
Propionyl-CoA: 45.6
2-Methylbutyryl-CoA: 44.4
Isobutyryl-CoA: 32.6
CHC-CoA: 29.4
trans-1,2-CPDA: 24.5
Ethylmalonyl-CoA: 23.9
Benzoyl-CoA: 19.2
fatty_acid: 18.3
Acetyl-CoA: 16.3
3-Methylbutyryl-CoA: 15.5

pltF

Search NORINE for peptide: strict or relaxed

AMP-binding (9..403): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLlYLAlVcK
Nearest Stachelhaus code:: iva
Stachelhaus code match:: 70% (weak)