BGC0000224 - 1 region(s) - antiSMASH results

BGC0000224 (Streptomyces griseus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	33,064	A-74528	Polyketide	96%

BGC0000224 - Region 1 - T2PKS

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Location: 1 - 33,064 nt. (total: 33,064 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000224.1	1.00	Polyketide	fredericamycin A	Streptomyces griseus
BGC0000190.1	0.55	Polyketide	A-74528	Streptomyces sp. SANK 61196
BGC0000248.1	0.41	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000215.1	0.32	Polyketide	curamycin	Streptomyces cyaneus
BGC0000885.1	0.31	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000228.1	0.31	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000231.1	0.30	Polyketide	griseusin	Streptomyces griseus
BGC0000846.1	0.28	Other	tabtoxin	Pseudomonas syringae
BGC0001197.1	0.28	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000888.1	0.28	Other	bacilysin	Bacillus sp. CS93

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000224.1	1.00	Polyketide	fredericamycin A	Streptomyces griseus
BGC0000190.1	0.82	Polyketide	A-74528	Streptomyces sp. SANK 61196
BGC0000248.1	0.73	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000215.1	0.65	Polyketide	curamycin	Streptomyces cyaneus
BGC0000885.1	0.65	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000228.1	0.64	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000231.1	0.64	Polyketide	griseusin	Streptomyces griseus
BGC0000846.1	0.62	Other	tabtoxin	Pseudomonas syringae
BGC0001197.1	0.62	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000888.1	0.61	Other	bacilysin	Bacillus sp. CS93

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 33064
Starter unit(s):: hexadienyl-CoA (Score: 1322.0; E-value: 0)
malonamyl-CoA (Score: 561.0; E-value: 0)
Malonyl elongations:: 11|12 (Score: 714.4; E-value: 7.3e-218)
Product class(es):: pentangular polyphenol
Product molecular weight(s):: hexadienyl-CoA_11: 512.59 Da
hexadienyl-CoA_12: 554.63 Da
malonamyl-CoA_11: 503.54 Da
malonamyl-CoA_12: 545.58 Da

AAQ08910.1: AT (Score: 422.9; E-value: 2.1e-129); AT AAQ08910.1_Fredericamycin_hexadienyl-CoA (Score: 664.0; E-value: 0.0)
AAQ08912.1: KR (Score: 232.0; E-value: 2.1e-71)
AAQ08914.1: CYC C4-C21/C2-C23|C2-C19 (Score: 173.1; E-value: 3e-54)
AAQ08915.1: CYC C5-C18 (Score: 212.3; E-value: 4.3e-66)
AAQ08916.1: KS (Score: 732.9; E-value: 2.3e-223)
AAQ08917.1: CLF 11|12 (Score: 714.4; E-value: 7.3e-218)
AAQ08918.1: ACP (Score: 99.5; E-value: 1.9e-31)
AAQ08919.1: CYC C9-C14 (Score: 251.1; E-value: 7.1e-78)
AAQ08925.1: MET C11O (Score: 552.4; E-value: 7.6e-169)
AAQ08926.1: KR C19 (Score: 431.3; E-value: 2.4e-132)
AAQ08929.1: KSIII (Score: 429.9; E-value: 1.5e-131); KSIII AAQ08929.1_Fredericamycin_hexadienyl-CoA (Score: 658.0; E-value: 0.0)
AAQ08933.1: AMID (Score: 779.5; E-value: 4.4e-237); AMID ELQ83270.1_Oxytetracycline_malonamyl-CoA (Score: 561.0; E-value: 0.0)