BGC0000727 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000727 (Streptomyces aureofaciens)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	29,395	auricin	Polyketide:Type II + Saccharide:Hybrid/tailoring	31%

BGC0000727 - Region 1 - NRPS-like

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Location: 1 - 29,395 nt. (total: 29,395 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 29,396
Label		BGC0000727

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000727.1	1.00	Saccharide	indigoidine	Streptomyces aureofaciens
BGC0000427.1	0.36	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.30	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.28	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.28	NRP	dimethylcoprogen	Alternaria alternata
BGC0001561.1	0.27	NRP	curacomycin	Streptomyces curacoi
BGC0001399.1	0.27	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000979.1	0.26	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.26	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000719.1	0.25	Saccharide	tobramycin	Streptoalloteichus hindustanus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000727.1	1.00	Saccharide	indigoidine	Streptomyces aureofaciens
BGC0000427.1	0.69	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.63	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.62	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.61	NRP	dimethylcoprogen	Alternaria alternata
BGC0001561.1	0.61	NRP	curacomycin	Streptomyces curacoi
BGC0001399.1	0.60	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000979.1	0.59	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.59	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000719.1	0.59	Saccharide	tobramycin	Streptoalloteichus hindustanus

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 29395:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

sa8

Search NORINE for peptide: strict or relaxed

AMP-binding (23..431): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGvInK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 80% (moderate)