BGC0000865 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000865 (Photobacterium profundum SS9)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	PUFA,hglE-KS	1	33,099	eicosapentaenoic acid	Other	44%

BGC0000865 - Region 1 - PUFA,hglE-KS

Download region GenBank file

Download region SVG

Location: 1 - 33,099 nt. (total: 33,099 nt) Show pHMM detection rules used

Region on contig edge.

PUFA: PUFA_KS
hglE-KS: (hglE or hglD)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 33,100
Label		BGC0000865

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000865.1	2.00	Other	eicoseicosapentaenoic acid	Photobacterium profundum SS9
BGC0000861.1	0.78	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000863.1	0.65	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000862.1	0.61	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0001144.1	0.50	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000869.1	0.48	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0000140.1	0.48	Polyketide	4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one	Streptomyces sp. 88-682
BGC0000048.1	0.47	Polyketide	dothistromin	Dothistroma septosporum
BGC0000161.1	0.47	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0000056.1	0.47	Polyketide	esperamicin	Actinomadura verrucosospora

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000865.1	1.00	Other	eicoseicosapentaenoic acid	Photobacterium profundum SS9
BGC0000861.1	0.71	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000863.1	0.66	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000862.1	0.64	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0001144.1	0.59	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000869.1	0.57	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0000140.1	0.57	Polyketide	4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one	Streptomyces sp. 88-682
BGC0000048.1	0.57	Polyketide	dothistromin	Dothistroma septosporum
BGC0000161.1	0.57	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0000056.1	0.57	Polyketide	esperamicin	Actinomadura verrucosospora

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 33099:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

AAL01056.1

Search NORINE for peptide: strict or relaxed

AMP-binding (19..466): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: --FFiasPLK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 50% (weak)

pfaA

PKS_AT (598..900): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 99.5
Methoxymalonyl-CoA: 31.9
inactive: 31.4
Methylmalonyl-CoA: 23.0
fatty_acid: 16.8
Isobutyryl-CoA: 13.6
Propionyl-CoA: 11.6
CHC-CoA: 10.5
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

pfaB

PKS_AT (326..630): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0