BGC0001124 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001124 (Aspergillus niger ATCC 1015)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	31,240

BGC0001124 - Region 1 - T1PKS

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Location: 1 - 31,240 nt. (total: 31,240 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 31,241
Label		BGC0001124

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001124.1	0.55	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0000046.1	0.33	Polyketide	depudecin	Alternaria brassicicola
BGC0001068.1	0.31	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001280.1	0.27	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.27	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000003.1	0.26	Polyketide	AF-toxin	Alternaria alternata
BGC0001909.1	0.23	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001899.1	0.21	Polyketide	abscisic acid	Leptosphaeria maculans JN3
BGC0000156.1	0.21	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001124.1	0.82	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0000046.1	0.66	Polyketide	depudecin	Alternaria brassicicola
BGC0001068.1	0.64	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001280.1	0.60	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.60	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000003.1	0.60	Polyketide	AF-toxin	Alternaria alternata
BGC0001909.1	0.57	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001899.1	0.54	Polyketide	abscisic acid	Leptosphaeria maculans JN3
BGC0000156.1	0.54	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger

Similar known gene clusters

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 30318:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ASPNIDRAFT_179585

PKS_AT (566..879): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 88.5
Methoxymalonyl-CoA: 85.2
Isobutyryl-CoA: 79.1
Malonyl-CoA: 68.2
Ethylmalonyl-CoA: 47.5
Propionyl-CoA: 45.7
Benzoyl-CoA: 39.1
inactive: 38.5
3-Methylbutyryl-CoA: 30.4
trans-1,2-CPDA: 26.0
2-Methylbutyryl-CoA: 24.2
Acetyl-CoA: 23.4
CHC-CoA: 11.7
fatty_acid: 10.7