BGC0001404 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001404 (Penicillium rubens Wisconsin 54-1255)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	28,758

BGC0001404 - Region 1 - T1PKS

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Location: 1 - 28,758 nt. (total: 28,758 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 28,759
Label		BGC0001404

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001404.1	1.00	Polyketide	sorbicillin	Penicillium rubens Wisconsin 54-1255
BGC0000099.1	0.37	Polyketide	monascorubrin	Talaromyces marneffei
BGC0000046.1	0.32	Polyketide	depudecin	Alternaria brassicicola
BGC0000013.1	0.31	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001144.1	0.29	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0001542.1	0.27	Polyketide	cercosporin	Cercospora zeina
BGC0000161.1	0.26	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0001541.1	0.25	Polyketide	cercosporin	Cercospora beticola
BGC0001068.1	0.23	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001858.1	0.23	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001404.1	1.00	Polyketide	sorbicillin	Penicillium rubens Wisconsin 54-1255
BGC0000099.1	0.70	Polyketide	monascorubrin	Talaromyces marneffei
BGC0000046.1	0.65	Polyketide	depudecin	Alternaria brassicicola
BGC0000013.1	0.65	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001144.1	0.63	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0001542.1	0.60	Polyketide	cercosporin	Cercospora zeina
BGC0000161.1	0.60	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0001541.1	0.58	Polyketide	cercosporin	Cercospora beticola
BGC0001068.1	0.57	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001858.1	0.56	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15

Similar known gene clusters

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 28758:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (pk) + (Me-pk)
Non-colinear ordering:: PCH_Pc21g05070 + PCH_Pc21g05080

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

PCH_Pc21g05070

PKS_AT (960..1255): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 58.3%; Methoxymalonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 65.8
Methylmalonyl-CoA: 53.4
Malonyl-CoA: 48.6
inactive: 37.7
Ethylmalonyl-CoA: 27.5
Propionyl-CoA: 27.1
CHC-CoA: 25.0
2-Methylbutyryl-CoA: 21.2
trans-1,2-CPDA: 17.2
Isobutyryl-CoA: 14.7
3-Methylbutyryl-CoA: 13.8
Benzoyl-CoA: 12.8
Acetyl-CoA: 12.1
fatty_acid: 0.0

PCH_Pc21g05080

PKS_AT (573..895): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%; Methylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 71.8
Methoxymalonyl-CoA: 63.3
Ethylmalonyl-CoA: 44.6
Isobutyryl-CoA: 38.5
Malonyl-CoA: 32.7
Propionyl-CoA: 25.0
trans-1,2-CPDA: 20.3
Benzoyl-CoA: 18.0
2-Methylbutyryl-CoA: 12.1
fatty_acid: 11.6
CHC-CoA: 10.8
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0