BGC0001622 - 1 region(s) - antiSMASH results

BGC0001622 (Streptomyces sp)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	23,603	rubrolone A / rubrolone B	Alkaloid	36%

BGC0001622 - Region 1 - T2PKS

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Location: 1 - 23,603 nt. (total: 23,603 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001622.1	1.00	Polyketide	isatropolone A, isotropolone B, isotropolone C	Streptomyces sp.
BGC0000248.1	0.36	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0002031.1	0.32	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0000272.1	0.28	Polyketide	spore pigment	Streptomyces collinus
BGC0000286.1	0.27	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0001858.1	0.26	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000215.1	0.25	Polyketide	curamycin	Streptomyces cyaneus
BGC0000231.1	0.25	Polyketide	griseusin	Streptomyces griseus
BGC0001903.1	0.25	Other	neocarazostatin A	Streptomyces sp. MA37
BGC0001224.1	0.25	Other	reductasporine	uncultured bacterium

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001622.1	1.00	Polyketide	isatropolone A, isotropolone B, isotropolone C	Streptomyces sp.
BGC0000248.1	0.68	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0002031.1	0.65	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0000272.1	0.61	Polyketide	spore pigment	Streptomyces collinus
BGC0000286.1	0.61	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0001858.1	0.60	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000215.1	0.59	Polyketide	curamycin	Streptomyces cyaneus
BGC0000231.1	0.58	Polyketide	griseusin	Streptomyces griseus
BGC0001903.1	0.58	Other	neocarazostatin A	Streptomyces sp. MA37
BGC0001224.1	0.58	Other	reductasporine	uncultured bacterium

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 23603
Starter unit(s):: butyryl-CoA (Score: 469.0; E-value: 5.21e-171)
2-methylbutyryl-CoA (Score: 211.0; E-value: 1.49e-66)
Malonyl elongations:: 7 (Score: 676.5; E-value: 2.6e-206)
Product molecular weight(s):: 2-methylbutyryl-CoA_7: 542.57 Da
butyryl-CoA_7: 528.55 Da

ARG41906.1: MET (Score: 32.2; E-value: 1.3e-10)
ARG41910.1: ACP (Score: 67.3; E-value: 2.1e-21)
ARG41911.1: KS (Score: 774.3; E-value: 6.3e-236)
ARG41912.1: CLF 7 (Score: 676.5; E-value: 2.6e-206)
ARG41914.1: GT (Score: 314.7; E-value: 2.7e-96)
ARG41916.1: CYC C7-C12 (Score: 122.3; E-value: 4.4e-38)
ARG41917.1: CYC C5-C14/C3-C16 (Score: 325.5; E-value: 5.6e-100)
ARG41919.1: ACP (Score: 67.8; E-value: 1.4e-21); OXY (Score: 389.5; E-value: 5.8e-119)
ARG41921.1: KSIII (Score: 390.2; E-value: 1.8e-119); KSIII ACI88883.1_Alnumycin_butyryl-CoA (Score: 469.0; E-value: 5.21e-171)
ARG41924.1: AT (Score: 363.9; E-value: 1.8e-111); AT ADB23379.1_TLN-05220/TLN-05223_2-methylbutyryl-CoA (Score: 211.0; E-value: 1.49e-66)