BGC0000007 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000007 (Aspergillus flavus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	82,511	aflatoxin	Polyketide	100%

BGC0000007 - Region 1 - T1PKS

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Location: 1 - 82,511 nt. (total: 82,511 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 82,512
Label		BGC0000007

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000007.1	0.48	Polyketide	aflatoxin	Aspergillus flavus
BGC0000009.1	0.35	Polyketide	aflatoxin	Aspergillus nomius
BGC0001068.1	0.28	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000006.1	0.27	Polyketide	aflatoxin	Aspergillus flavus
BGC0000004.1	0.27	Polyketide	aflatoxin G1	Aspergillus oryzae
BGC0000008.1	0.27	Polyketide	aflatoxin	Aspergillus flavus
BGC0000676.1	0.27	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0000048.1	0.25	Polyketide	dothistromin	Dothistroma septosporum
BGC0000010.1	0.24	Polyketide	aflatoxin	Aspergillus flavus
BGC0000003.1	0.22	Polyketide	AF-toxin	Alternaria alternata

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000007.1	0.87	Polyketide	aflatoxin	Aspergillus flavus
BGC0000010.1	0.86	Polyketide	aflatoxin	Aspergillus flavus
BGC0000008.1	0.80	Polyketide	aflatoxin	Aspergillus flavus
BGC0000006.1	0.80	Polyketide	aflatoxin	Aspergillus flavus
BGC0000004.1	0.80	Polyketide	aflatoxin G1	Aspergillus oryzae
BGC0000009.1	0.78	Polyketide	aflatoxin	Aspergillus nomius
BGC0000005.1	0.74	Polyketide	aflatoxin	Aspergillus parasiticus
BGC0001858.1	0.63	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.61	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001910.1	0.56	Terpene	cyslabdan	Streptomyces cyslabdanicus

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 46450:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

AAS89999.1

PKS_AT (904..1199): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 120.1
inactive: 58.8
Methoxymalonyl-CoA: 53.5
Methylmalonyl-CoA: 46.7
Isobutyryl-CoA: 27.0
Propionyl-CoA: 25.9
fatty_acid: 18.5
2-Methylbutyryl-CoA: 18.5
Acetyl-CoA: 15.4
Ethylmalonyl-CoA: 14.8
CHC-CoA: 14.0
Benzoyl-CoA: 11.0
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

AAS90002.1

PKS_AT (138..380): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (1518..1709): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0