BGC0000048 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000048 (Dothistroma septosporum (Mycosphaerella pini))

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	52,829	sterigmatocystin	Polyketide	15%

BGC0000048 - Region 1 - T1PKS

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Location: 1 - 52,829 nt. (total: 52,829 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 52,830
Label		BGC0000048

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000048.1	0.56	Polyketide	dothistromin	Dothistroma septosporum
BGC0001068.1	0.28	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000046.1	0.26	Polyketide	depudecin	Alternaria brassicicola
BGC0001583.1	0.23	Polyketide	emodin	Escovopsis weberi
BGC0000107.1	0.22	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001265.1	0.22	Polyketide	melanin	Bipolaris oryzae
BGC0001257.1	0.22	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001906.1	0.22	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001266.1	0.22	Polyketide	grayanic acid	Cladonia grayi
BGC0000030.1	0.21	Polyketide	bikaverin	Fusarium fujikuroi IMI 58289

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000048.1	0.87	Polyketide	dothistromin	Dothistroma septosporum
BGC0001068.1	0.61	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000046.1	0.60	Polyketide	depudecin	Alternaria brassicicola
BGC0001910.1	0.56	Terpene	cyslabdan	Streptomyces cyslabdanicus
BGC0001583.1	0.56	Polyketide	emodin	Escovopsis weberi
BGC0000003.1	0.56	Polyketide	AF-toxin	Alternaria alternata
BGC0001865.1	0.55	Polyketide	elsinochrome C	Parastagonospora nodorum SN15
BGC0001911.1	0.55	Terpene	raimonol	Streptomyces anulatus
BGC0001542.1	0.55	Polyketide	cercosporin	Cercospora zeina
BGC0000107.1	0.55	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 15724 - 52829:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

pksA

PKS_AT (906..1202): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 128.6
inactive: 65.8
Methoxymalonyl-CoA: 57.5
Methylmalonyl-CoA: 53.3
Propionyl-CoA: 34.3
Isobutyryl-CoA: 23.9
CHC-CoA: 22.8
Ethylmalonyl-CoA: 19.7
fatty_acid: 19.0
2-Methylbutyryl-CoA: 15.3
Acetyl-CoA: 12.4
Benzoyl-CoA: 9.0
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0