Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000166.1:
Cluster 1Polyketide143280

BGC0000166, tylactone biosynthetic gene cluster from Streptomyces fradiae. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: tylactone

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Type I

Gene cluster description

tylactone (BGC0000166). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank U78289. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Castonguay R et al. (2008) Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. J Am Chem Soc 130(35):11598-9. doi: 10.1021/ja804453p. Epub 2008 Aug