BGC0000235: kiamycin biosynthetic gene cluster from Streptomyces sp. W007
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Location: 118,282 - 139,606 nt. (total: 21,325 nt).
This entry is originally from NCBI GenBank AGSW01000147.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000235
Short description kiamycin biosynthetic gene cluster from Streptomyces sp. W007
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AGSW01000147.1
118282 - 139606
via
Compounds
  • kiamycin
Species Streptomyces sp. W007 [taxonomy]
References
Chemical products information
kiamycin Evidence:
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C20H18O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SPW_4216
  • EHM27493.1
 118282 - 119031 (+) ABC transporter related protein
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    • SPW_4217
    • EHM27494.1
    		 119072 - 119911 (+) putative SAM-dependent methyltransferase
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      • SPW_4218
      • EHM27495.1
      		 120028 - 120468 (+) hypothetical protein
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        • SPW_4219
        • EHM27496.1
        		 120529 - 121335 (-) putative secreted hydrolase
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          • SPW_4220
          • EHM27497.1
          		 121832 - 122614 (-) putative short-chain dehydrogenase/reductase
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            • SPW_4221
            • EHM27498.1
            		 123532 - 124197 (+) two component LuxR family transcriptional regulator
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              • SPW_4222
              • EHM27499.1
              		 124238 - 124945 (-) putative short chain oxidoreductase
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                • SPW_4223
                • EHM27500.1
                		 125036 - 125704 (-) TetR family transcriptional regulator
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                  • SPW_4224
                  • EHM27501.1
                  		 125908 - 127320 (+) putative export protein
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                    • SPW_4225
                    • EHM27502.1
                    		 127711 - 128646 (+) O-methyltransferase family protein
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                      • SPW_4226
                      • EHM27503.1
                      		 128727 - 130229 (+) monooxygenase FAD-binding
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                        • SPW_4227
                        • EHM27504.1
                        		 130297 - 130596 (+) polyketide synthesis cyclase
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                          • SPW_4228
                          • EHM27505.1
                          		 130593 - 131873 (+) ketoacyl synthase
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                            • SPW_4229
                            • EHM27506.1
                            		 131870 - 133090 (+) chain length determinant protein
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                              • SPW_4230
                              • EHM27507.1
                              		 133148 - 133417 (+) acyl carrier protein
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                                • SPW_4231
                                • EHM27508.1
                                		 133470 - 134240 (+) short-chain dehydrogenase/reductase SDR
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                                  • SPW_4232
                                  • EHM27509.1
                                  		 134276 - 135247 (+) cyclase/dehydrase
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                                    • SPW_4233
                                    • EHM27510.1
                                    		 135251 - 137221 (+) monooxygenase FAD-binding
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                                      • SPW_4234
                                      • EHM27511.1
                                      		 137259 - 138023 (+) putative short chain dehydrogenase
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                                        • SPW_4235
                                        • EHM27512.1
                                        		 138029 - 139606 (+) carboxyl transferase
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                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: 4

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Update chemical activity to schema version 2.11
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Updated bioactivity data
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2019-10-16
                                          Migrated from v1.4
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2019-10-16
                                          Updated compound(s) information (NPAtlas curation)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2015-06-12
                                          Submitted
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Detailed domain annotation
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