Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000991.1:
Cluster 1NRP / Polyketide158733

BGC0000991, epothilone biosynthetic gene cluster from Sorangium cellulosum. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: epothilone
PubChem ID: 448013
SMILES string: Copy to clipboard
Molecular formula: C27H41NO6S
Average molecular mass: 507.686 Da

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

epothilone (BGC0000991). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank AF217189. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Tang L et al. (2000) Cloning and heterologous expression of the epothilone gene cluster. Science 287(5453):640-2.
2. Julien B et al. (2000) Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum. Gene 249(1-2):153-60.