BGC0001677 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001677 (Penicillium roqueforti)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	23,325	mycophenolic acid	Terpene + Polyketide:Iterative type I	87%

BGC0001677 - Region 1 - T1PKS

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Location: 1 - 23,325 nt. (total: 23,325 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 23,326
Label		BGC0001677

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001677.1	1.00	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0001360.1	0.50	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0000104.1	0.42	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001068.1	0.31	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000682.1	0.30	Terpene	terretonin	Aspergillus terreus NIH2624
BGC0001508.1	0.28	Polyketide	andrastin A	Penicillium roqueforti
BGC0001708.1	0.26	Polyketide, Terpene	novofumigatonin	Aspergillus novofumigatus IBT 16806
BGC0001729.1	0.25	Polyketide, Terpene	paraherquonin	Penicillium brasilianum
BGC0000037.1	0.22	Polyketide	cichorine	Aspergillus nidulans FGSC A4
BGC0001304.1	0.18	Polyketide	aflavarin	Aspergillus flavus NRRL3357

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001677.1	1.00	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0001360.1	0.79	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0000104.1	0.73	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001068.1	0.65	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000682.1	0.64	Terpene	terretonin	Aspergillus terreus NIH2624
BGC0001508.1	0.62	Polyketide	andrastin A	Penicillium roqueforti
BGC0001708.1	0.60	Polyketide, Terpene	novofumigatonin	Aspergillus novofumigatus IBT 16806
BGC0001729.1	0.58	Polyketide, Terpene	paraherquonin	Penicillium brasilianum
BGC0000037.1	0.55	Polyketide	cichorine	Aspergillus nidulans FGSC A4
BGC0001304.1	0.50	Polyketide	aflavarin	Aspergillus flavus NRRL3357

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23325:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

mpaC

PKS_AT (747..1037): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 84.1
inactive: 63.8
Methoxymalonyl-CoA: 41.2
Methylmalonyl-CoA: 36.5
fatty_acid: 18.7
Ethylmalonyl-CoA: 15.8
Propionyl-CoA: 15.5
CHC-CoA: 15.2
Benzoyl-CoA: 13.0
Acetyl-CoA: 12.6
2-Methylbutyryl-CoA: 11.5
trans-1,2-CPDA: 11.1
Isobutyryl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0