BGC0001708 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001708 (Aspergillus novofumigatus IBT 16806)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	32,997	paraherquonin	Polyketide + Terpene	43%

BGC0001708 - Region 1 - T1PKS

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Location: 1 - 32,997 nt. (total: 32,997 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 32,998
Label		BGC0001708

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001708.1	1.00	Polyketide, Terpene	novofumigatonin	Aspergillus novofumigatus IBT 16806
BGC0001677.1	0.28	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001280.1	0.22	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.22	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001360.1	0.22	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0000156.1	0.21	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0001141.1	0.21	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0001284.1	0.21	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0000121.1	0.21	Polyketide	RES-1214-2	Pestalotiopsis fici

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001708.1	1.00	Polyketide, Terpene	novofumigatonin	Aspergillus novofumigatus IBT 16806
BGC0001677.1	0.62	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001280.1	0.55	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.55	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001360.1	0.55	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0000156.1	0.54	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0001141.1	0.54	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0001284.1	0.54	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0000121.1	0.54	Polyketide	RES-1214-2	Pestalotiopsis fici

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 5866 - 32997:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

P174DRAFT_455569

PKS_AT (887..1172): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 67.2
inactive: 41.4
Methoxymalonyl-CoA: 39.6
Methylmalonyl-CoA: 30.9
fatty_acid: 18.0
Propionyl-CoA: 16.1
2-Methylbutyryl-CoA: 12.9
Benzoyl-CoA: 10.9
CHC-CoA: 10.6
Ethylmalonyl-CoA: 10.5
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0