BGC0001717: okaramine B biosynthetic gene cluster from Penicillium simplicissimum
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Location: 2,899 - 22,560 nt. (total: 19,662 nt).
This entry is originally from NCBI GenBank LC316945.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001717
Short description okaramine B biosynthetic gene cluster from Penicillium simplicissimum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LC316945.1
2899 - 22560
via
Compounds
  • okaramine B
Species Penicillium simplicissimum [taxonomy]
References
Chemical products information
okaramine B Evidence:
Copy SMILES
C33H34N4O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBB04327.1
  • okaA
 2899 - 8973 (-) nonribosomal peptide synthetase
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    • BBB04328.1
    • okaB
    		 9879 - 11460 (+) flavin monooxygenase
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      • BBB04329.1
      • okaC
      		 11859 - 13213 (-) dimethylallyltryptophan synthase
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        • BBB04330.1
        • okaD
        		 13714 - 15303 (+) cytochrome P450
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          • BBB04331.1
          • okaE
          		 16381 - 17283 (+) alpha-ketoglutarate-dependent dioxygenase
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            • BBB04332.1
            • okaF
            		 18877 - 20255 (+) methyltransferase
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              • BBB04333.1
              • okaG
              		 20674 - 22560 (-) cytochrome P450
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                Biosynthesis information

                Biosynthetic modules

                Name
                Unk01
                Type
                nrps-type1
                Genes
                okaA
                Substrates
                tryptophan (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Annotation changelog

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                2022-09-15
                Fix biosynthetic class
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                2022-09-15
                Added NRP substrate specificities
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                2019-10-16
                Migrated from v1.4
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                2019-10-16
                Updated compound(s) information (NPAtlas curation)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                2018-08-06
                Submitted
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
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