BGC0002034 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002034 (Streptomyces sp. IB2014 016-6)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T3PKS	1	41,206	High	perquinoline A/perquinoline B/perquinoline C	other:other

BGC0002034 - Region 1 - T3PKS

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Location: 1 - 41,206 nt. (total: 41,206 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 41,207
Label		BGC0002034

Tailoring functions

Transferases: aminotransferase formyltransferase

EW053_28345: aminotransferase

smcogs: SMCOG1019: aminotransferase

EW053_28400: methionyl-tRNA formyltransferase

smcogs: SMCOG1228: methionyl-tRNA formyltransferase

Lyases: hydratase

EW053_28350: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

EW053_28355: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

EW053_28375: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

Ligases: synthase

EW053_28360: chalcone and stilbene synthase domain protein

smcogs: SMCOG1024: chalcone and stilbene synthase domain protein

EW053_28365: 8-amino-7-oxononanoate synthase

smcogs: SMCOG1109: 8-amino-7-oxononanoate synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002034.3	1.00	other (other)	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0002127.3	0.47	PKS	flaviolin, 1,3,6,8-tetrahydroxynaphthalene	Streptomyces coelicolor A3(2)
BGC0001148.5	0.45	NRPS, ribosomal	pheganomycin	Streptomyces cirratus
BGC0000273.5	0.45	PKS, saccharide	steffimycin D	Streptomyces steffisburgensis
BGC0001659.3	0.43	terpene	mangicol A	Fusarium equiseti
BGC0000243.4	0.40	PKS	nonactin, monactin, dinactin, trinactin, tetranactin	Streptomyces griseus subsp. griseus
BGC0001633.3	0.40	other (other)	ketomemicin B3, ketomemicin B4	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001233.5	0.38	NRPS	feglymycin	Streptomyces sp. DSM 11171
BGC0002314.3	0.36	NRPS	corbomycin	Streptomyces sp. WAC 01529
BGC0001066.5	0.36	PKS	kendomycin	Streptomyces violaceoruber

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002034.3	1.00	other (other)	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0002127.3	0.47	PKS	flaviolin, 1,3,6,8-tetrahydroxynaphthalene	Streptomyces coelicolor A3(2)
BGC0001148.5	0.45	NRPS, ribosomal	pheganomycin	Streptomyces cirratus
BGC0000273.5	0.45	PKS, saccharide	steffimycin D	Streptomyces steffisburgensis
BGC0001659.3	0.43	terpene	mangicol A	Fusarium equiseti
BGC0000243.4	0.40	PKS	nonactin, monactin, dinactin, trinactin, tetranactin	Streptomyces griseus subsp. griseus
BGC0001633.3	0.40	other (other)	ketomemicin B3, ketomemicin B4	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001233.5	0.38	NRPS	feglymycin	Streptomyces sp. DSM 11171
BGC0002314.3	0.36	NRPS	corbomycin	Streptomyces sp. WAC 01529
BGC0001066.5	0.36	PKS	kendomycin	Streptomyces violaceoruber

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS substrates

NRPS/PKS substrate predictions

EW053_28370: X

AMP-binding (104..305): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: AQTILIFSYK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

Link to PARAS substrate predictor