BGC0002074: huascopeptin biosynthetic gene cluster from Streptomyces huasconensis
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Location: 1 - 2,630 nt. (total: 2,630 nt).
This entry is originally from NCBI GenBank MK636692.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002074
Short description huascopeptin biosynthetic gene cluster from Streptomyces huasconensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "The huascopeptin is a 13-residue class II lasso peptide containing the first Gly1-Asp7 macrolactam ring. This lasso peptide was isolated from Streptomyces huasconensis HST28 from Salar de Huasco, Atacama Desert, Chile and it represents the smallest macrocycle opening isolated to date with 22 atoms (One less than the xanthomonins)."
Biosynthetic class(es)
  • RiPP (Lassopeptide)
Loci NCBI GenBank: MK636692.1
Compounds
  • huascopeptin
Species Streptomyces huasconensis [taxonomy]
References
Chemical products information
huascopeptin
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C65H87N17O19
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QCY49166.1
  • hptA
 1 - 135 (+) lasso peptide precursor
  • Precursor biosynthesis
Sequence-based prediction
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  • QCY49167.1
  • hptC
 150 - 1991 (+) lasso peptide cyclase
  • Precursor biosynthesis
Sequence-based prediction
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  • QCY49168.1
  • hptB1
 1969 - 2229 (+) RiPP recognition element
  • Precursor biosynthesis
Sequence-based prediction
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  • QCY49169.1
  • hptB2
 2226 - 2630 (+) lasso peptide protease
  • Precursor biosynthesis
Sequence-based prediction
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RiPP-specific information
Subclass Lassopeptide
Cyclic? yes
Peptidases
    hptB2
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: 3BAEWLAJEJZVIT7VC2LDIRNV, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
  • Added version to NCBI accession
  • Fix peptidase gene ID
Similar known gene clusters
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