BGC0002074: huascopeptin biosynthetic gene cluster from Streptomyces huasconensis
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Location: 1 - 2,630 nt. (total: 2,630 nt).
This entry is originally from NCBI GenBank MK636692.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002074
Short description huascopeptin biosynthetic gene cluster from Streptomyces huasconensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "The huascopeptin is a 13-residue class II lasso peptide containing the first Gly1-Asp7 macrolactam ring. This lasso peptide was isolated from Streptomyces huasconensis HST28 from Salar de Huasco, Atacama Desert, Chile and it represents the smallest macrocycle opening isolated to date with 22 atoms (One less than the xanthomonins)."
Biosynthetic class(es)
  • ribosomal (unmodified)
Loci
MK636692.1
via Gene expression correlated with compound production
Compounds
  • huascopeptin
Species Streptomyces huasconensis [taxonomy]
References
Chemical products information
huascopeptin Evidence: NMR, Mass spectrometry
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C65H87N17O19
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QCY49166.1
  • hptA
 1 - 135 (+) lasso peptide precursor
  • Precursor biosynthesis
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  • QCY49167.1
  • hptC
 150 - 1991 (+) lasso peptide cyclase
  • Precursor biosynthesis
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  • QCY49168.1
  • hptB1
 1969 - 2229 (+) RiPP recognition element
  • Precursor biosynthesis
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  • QCY49169.1
  • hptB2
 2226 - 2630 (+) lasso peptide protease
  • Precursor biosynthesis
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Biosynthesis information
Annotation changelog

Entry version: 1

Date
Changes
Submitters
Reviewers
2022-09-15
Submitted
  • (ID: 3BAEWLAJEJZVIT7VC2LDIRNV)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Added version to NCBI accession
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Fix peptidase gene ID
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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