BGC0000432 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000432 (Streptomyces rochei)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	34,051	BD-12	NRP	57%

BGC0000432 - Region 1 - NRPS-like

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Location: 1 - 34,051 nt. (total: 34,051 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 34,052
Label		BGC0000432

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000432.1	0.91	NRP	streptothricin	Streptomyces rochei
BGC0000375.1	0.32	NRP	indigoidine	Streptomyces chromofuscus
BGC0000348.1	0.32	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001399.1	0.32	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001249.1	0.31	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900.1	0.31	Other	ferrichrome	Aspergillus oryzae
BGC0000427.1	0.31	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001561.1	0.30	NRP	curacomycin	Streptomyces curacoi
BGC0000876.1	0.30	Other	neopolyoxin C	Streptomyces tendae
BGC0000921.1	0.27	Other, Polyketide, NRP, , (, S, h, i, k, i, m, a, t, e, -, d, e, r, i, v, e, d, )	promysalin	Pseudomonas putida

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000432.1	0.97	NRP	streptothricin	Streptomyces rochei
BGC0000375.1	0.66	NRP	indigoidine	Streptomyces chromofuscus
BGC0000348.1	0.65	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001399.1	0.65	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001249.1	0.65	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900.1	0.65	Other	ferrichrome	Aspergillus oryzae
BGC0000427.1	0.64	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001561.1	0.63	NRP	curacomycin	Streptomyces curacoi
BGC0000876.1	0.63	Other	neopolyoxin C	Streptomyces tendae
BGC0000921.1	0.61	Other, Polyketide, NRP, , (, S, h, i, k, i, m, a, t, e, -, d, e, r, i, v, e, d, )	promysalin	Pseudomonas putida

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 34051:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

BAL15718.1

Search NORINE for peptide: strict or relaxed

AMP-binding (11..403): lys-b

NRPSPredictor2: lys-b

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DTEVVGTLVK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 100% (strong)

BAL15726.1

Search NORINE for peptide: strict or relaxed

AMP-binding (15..418): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVeeVGVVsK
Nearest Stachelhaus code:: trp
Stachelhaus code match:: 70% (weak)

BAL15732.1

Search NORINE for peptide: strict or relaxed

AMP-binding (9..419): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DTEnVGTLVK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 90% (moderate)