BGC0001360 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001360 (Penicillium roqueforti FM164)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	23,175	mycophenolic acid	Polyketide	100%

BGC0001360 - Region 1 - T1PKS

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Location: 1 - 23,175 nt. (total: 23,175 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 23,176
Label		BGC0001360

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001360.1	1.00	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0001677.1	0.49	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0000104.1	0.36	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001508.1	0.27	Polyketide	andrastin A	Penicillium roqueforti
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000682.1	0.22	Terpene	terretonin	Aspergillus terreus NIH2624
BGC0001708.1	0.21	Polyketide, Terpene	novofumigatonin	Aspergillus novofumigatus IBT 16806
BGC0000156.1	0.21	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0000057.1	0.20	Polyketide	F9775A, F9775B, orsellinic acid	Aspergillus nidulans FGSC A4
BGC0001265.1	0.20	Polyketide	melanin	Bipolaris oryzae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001360.1	1.00	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0001677.1	0.78	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0000104.1	0.68	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001508.1	0.60	Polyketide	andrastin A	Penicillium roqueforti
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000682.1	0.55	Terpene	terretonin	Aspergillus terreus NIH2624
BGC0001708.1	0.53	Polyketide, Terpene	novofumigatonin	Aspergillus novofumigatus IBT 16806
BGC0000156.1	0.53	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0000057.1	0.53	Polyketide	F9775A, F9775B, orsellinic acid	Aspergillus nidulans FGSC A4
BGC0001265.1	0.53	Polyketide	melanin	Bipolaris oryzae

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23175:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

PROQFM164_S05g000559

PKS_AT (930..1220): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 84.1
inactive: 63.8
Methoxymalonyl-CoA: 41.2
Methylmalonyl-CoA: 36.5
fatty_acid: 18.7
Ethylmalonyl-CoA: 15.8
Propionyl-CoA: 15.5
CHC-CoA: 15.2
Benzoyl-CoA: 13.0
Acetyl-CoA: 12.6
2-Methylbutyryl-CoA: 11.5
trans-1,2-CPDA: 11.1
Isobutyryl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0