BGC0001729 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001729 (Penicillium brasilianum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	47,451	terretonin	Terpene	60%

BGC0001729 - Region 1 - T1PKS

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Location: 1 - 47,451 nt. (total: 47,451 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 47,452
Label		BGC0001729

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001729.1	0.95	Polyketide, Terpene	paraherquonin	Penicillium brasilianum
BGC0000104.1	0.34	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001909.1	0.31	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001677.1	0.29	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0001475.1	0.25	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0001068.1	0.23	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001280.1	0.22	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.22	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001995.1	0.22	Terpene	heptelidic acid	Aspergillus oryzae RIB40

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001729.1	1.00	Polyketide, Terpene	paraherquonin	Penicillium brasilianum
BGC0000104.1	0.67	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001909.1	0.64	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001677.1	0.63	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0001969.1	0.62	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0001811.1	0.62	Terpene	trichodiene-11-one	Fusarium asiaticum
BGC0001277.1	0.62	Terpene	nivalenol, vomitoxin, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, neosolaniol, calonectrin, apotrichodiol, isotrichotriol, 15-deacetylcalonectrin, T-2 toxin, 3-acetyl T-2 toxin, trichodiene	Fusarium graminearum
BGC0000930.1	0.62	Other	deoxynivalenol	Fusarium graminearum
BGC0001858.1	0.58	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000631.1	0.58	Terpene	botrydial	Botrytis cinerea B05.10

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 9561 - 47451:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

prhL

PKS_AT (910..1195): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 69.1
inactive: 44.8
Methoxymalonyl-CoA: 44.6
Methylmalonyl-CoA: 29.7
Ethylmalonyl-CoA: 21.7
Benzoyl-CoA: 20.8
Propionyl-CoA: 15.2
fatty_acid: 13.3
2-Methylbutyryl-CoA: 12.7
CHC-CoA: 12.6
Isobutyryl-CoA: 8.5
3-Methylbutyryl-CoA: 4.9
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0