BGC0000070 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000070 (Penicillium aethiopicum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	55,000	alternariol	Terpene	100%

BGC0000070 - Region 1 - T1PKS

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Location: 1 - 55,000 nt. (total: 55,000 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 55,001
Label		BGC0000070

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000070.1	0.67	Polyketide	griseofulvin, epidechlorogriseofulvin, norlichexanthone, dehydrogriseofulvin, 4-desmethylgriseofulvin, griseoxanthone B	Penicillium aethiopicum
BGC0001858.1	0.28	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001284.1	0.27	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001280.1	0.24	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.24	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001405.1	0.23	Polyketide	chaetoviridin E, 11-epichaetomugilin A	Chaetomium globosum CBS 148.51
BGC0000688.1	0.23	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000156.1	0.22	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0001265.1	0.22	Polyketide	melanin	Bipolaris oryzae
BGC0001583.1	0.22	Polyketide	emodin	Escovopsis weberi

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000070.1	0.87	Polyketide	griseofulvin, epidechlorogriseofulvin, norlichexanthone, dehydrogriseofulvin, 4-desmethylgriseofulvin, griseoxanthone B	Penicillium aethiopicum
BGC0001858.1	0.61	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001284.1	0.61	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001280.1	0.58	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.58	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001405.1	0.57	Polyketide	chaetoviridin E, 11-epichaetomugilin A	Chaetomium globosum CBS 148.51
BGC0000688.1	0.56	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000156.1	0.55	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0001265.1	0.55	Polyketide	melanin	Bipolaris oryzae
BGC0001583.1	0.55	Polyketide	emodin	Escovopsis weberi

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1524 - 47196:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ADI24953.1

PKS_AT (923..1219): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 50.4
Malonyl-CoA: 50.3
Methylmalonyl-CoA: 43.0
inactive: 22.2
Ethylmalonyl-CoA: 19.7
Benzoyl-CoA: 15.8
fatty_acid: 15.6
Propionyl-CoA: 12.8
CHC-CoA: 10.7
2-Methylbutyryl-CoA: 10.4
Acetyl-CoA: 8.7
Isobutyryl-CoA: 8.1
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0