BGC0000120 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000120 (Penicillium expansum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	40,217	terreic acid	Polyketide	33%

BGC0000120 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 1 - 40,217 nt. (total: 40,217 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 40,218
Label		BGC0000120

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000120.1	0.55	Polyketide	patulin	Penicillium expansum
BGC0000046.1	0.32	Polyketide	depudecin	Alternaria brassicicola
BGC0001858.1	0.31	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.28	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000003.1	0.25	Polyketide	AF-toxin	Alternaria alternata
BGC0001276.1	0.23	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.1	0.22	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273.1	0.22	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244.1	0.21	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001124.1	0.21	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000120.1	0.87	Polyketide	patulin	Penicillium expansum
BGC0001858.1	0.64	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.61	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000003.1	0.58	Polyketide	AF-toxin	Alternaria alternata
BGC0001141.1	0.57	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0001276.1	0.56	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001275.1	0.55	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273.1	0.55	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244.1	0.54	Polyketide	(-)-Mellein	Parastagonospora nodorum

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 14612 - 40217:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

patK

PKS_AT (568..859): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 112.4
Methoxymalonyl-CoA: 91.8
Ethylmalonyl-CoA: 86.8
Isobutyryl-CoA: 77.0
Malonyl-CoA: 67.1
Propionyl-CoA: 47.3
Acetyl-CoA: 42.0
2-Methylbutyryl-CoA: 38.4
trans-1,2-CPDA: 33.9
3-Methylbutyryl-CoA: 29.8
fatty_acid: 25.8
Benzoyl-CoA: 22.8
CHC-CoA: 11.2
inactive: 8.3