BGC0000327 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000327 (Streptomyces ambofaciens ATCC 23877)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	29,143	zorbamycin	NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring	6%

BGC0000327 - Region 1 - NRPS

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Location: 1 - 29,143 nt. (total: 29,143 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 29,144
Label		BGC0000327

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000327.1	0.86	NRP	netropsin	Streptomyces ambofaciens ATCC 23877
BGC0000427.1	0.33	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000348.1	0.31	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001249.1	0.31	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900.1	0.31	Other	ferrichrome	Aspergillus oryzae
BGC0000375.1	0.30	NRP	indigoidine	Streptomyces chromofuscus
BGC0001379.1	0.29	NRP	BD-12	Streptomyces luteocolor
BGC0000876.1	0.29	Other	neopolyoxin C	Streptomyces tendae
BGC0001479.1	0.28	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001517.1	0.27	NRP	asperphenamate	Aspergillus terreus NIH2624

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000327.1	0.97	NRP	netropsin	Streptomyces ambofaciens ATCC 23877
BGC0002042.1	0.75	NRP	anthelvencin A, anthelvencin B, anthelvencin C	Streptomyces venezuelae
BGC0000375.1	0.67	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.66	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001399.1	0.66	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000348.1	0.65	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001249.1	0.65	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900.1	0.64	Other	ferrichrome	Aspergillus oryzae
BGC0000876.1	0.62	Other	neopolyoxin C	Streptomyces tendae
BGC0001479.1	0.61	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23627:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

SAMR0901

Search NORINE for peptide: strict or relaxed

AMP-binding (25..432): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: sVeqVGEVsK
Nearest Stachelhaus code:: trp
Stachelhaus code match:: 60% (weak)

SAMR0921

Search NORINE for peptide: strict or relaxed

AMP-binding (21..433): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: sfAVlsVvIK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 50% (weak)