BGC0000347 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000347 (Streptococcus equi subsp. equi)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	23,813

BGC0000347 - Region 1 - NRPS

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Location: 1 - 23,813 nt. (total: 23,813 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 23,814
Label		BGC0000347

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000347.1	0.92	NRP	equibactin	Streptococcus equi subsp. equi
BGC0000412.1	0.30	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0002091.1	0.24	NRP	holomycin	Yersinia ruckeri ATCC 29473
BGC0000352.1	0.24	NRP	fimsbactin A	Acinetobacter sp. ADP1
BGC0000373.1	0.24	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001636.1	0.23	NRP	KK-1	Curvularia clavata
BGC0001538.1	0.21	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000343.1	0.21	NRP	enterobactin	Pseudomonas sp. J465
BGC0001873.1	0.20	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0001843.1	0.20	NRP	tridecaptin M	Paenibacillus sp. M-152

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000347.1	0.97	NRP	equibactin	Streptococcus equi subsp. equi
BGC0000412.1	0.64	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0002091.1	0.58	NRP	holomycin	Yersinia ruckeri ATCC 29473
BGC0000352.1	0.58	NRP	fimsbactin A	Acinetobacter sp. ADP1
BGC0000373.1	0.57	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001636.1	0.56	NRP	KK-1	Curvularia clavata
BGC0001538.1	0.54	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000343.1	0.53	NRP	enterobactin	Pseudomonas sp. J465
BGC0001873.1	0.52	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0001843.1	0.52	NRP	tridecaptin M	Paenibacillus sp. M-152

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23813:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

SEQ1243

Search NORINE for peptide: strict or relaxed

AMP-binding (29..433): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: dhb, sal
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: PLPgQGiilK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 60% (weak)

SEQ1242

Search NORINE for peptide: strict or relaxed

AMP-binding (554..956): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYdMSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)