BGC0001508 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001508 (Penicillium roqueforti)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	29,400	paraherquonin	Polyketide + Terpene	37%

BGC0001508 - Region 1 - T1PKS

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Location: 1 - 29,400 nt. (total: 29,400 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 29,401
Label		BGC0001508

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001508.1	1.00	Polyketide	andrastin A	Penicillium roqueforti
BGC0000104.1	0.36	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001360.1	0.33	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0001677.1	0.31	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0001909.1	0.30	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000676.1	0.23	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0001280.1	0.22	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.22	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000685.1	0.22	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0000688.1	0.21	Terpene	copalyl diphosphate	Diaporthe amygdali

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001508.1	1.00	Polyketide	andrastin A	Penicillium roqueforti
BGC0000104.1	0.69	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0001360.1	0.66	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0001677.1	0.64	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0001909.1	0.64	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000676.1	0.57	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0001280.1	0.55	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.55	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000685.1	0.55	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0000688.1	0.54	Terpene	copalyl diphosphate	Diaporthe amygdali

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 29400:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

adrD

PKS_AT (913..1203): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 69.8
inactive: 51.5
Methoxymalonyl-CoA: 49.8
Methylmalonyl-CoA: 36.0
Propionyl-CoA: 13.7
Ethylmalonyl-CoA: 13.6
CHC-CoA: 11.9
2-Methylbutyryl-CoA: 11.6
Benzoyl-CoA: 10.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0