BGC0001872 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001872 (Xenorhabdus bovienii SS-2004)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	hglE-KS,PUFA	1	20,491	fabclavine Ia	NRP + Polyketide	64%

BGC0001872 - Region 1 - PUFA,hglE-KS

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Location: 1 - 20,491 nt. (total: 20,491 nt) Show pHMM detection rules used

Region on contig edge.

hglE-KS: (hglE or hglD)
PUFA: PUFA_KS

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 20,492
Label		BGC0001872

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001872.1	2.00	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000863.1	0.58	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000161.1	0.55	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0001338.1	0.53	Polyketide	citrinin	Monascus ruber
BGC0000027.1	0.53	Polyketide	ankaflavin, monascin, rubropunctatine, monascorubrin	Monascus pilosus
BGC0001976.1	0.51	Terpene	eupenifeldin	Phoma sp.
BGC0001977.1	0.51	Other	eupenifeldin	Phoma sp.
BGC0001144.1	0.50	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0001399.1	0.50	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000861.1	0.49	Other	eicosapentaenoic acid	Shewanella sp. BR-2

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001872.1	1.00	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000863.1	0.63	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000161.1	0.61	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0001338.1	0.60	Polyketide	citrinin	Monascus ruber
BGC0000027.1	0.60	Polyketide	ankaflavin, monascin, rubropunctatine, monascorubrin	Monascus pilosus
BGC0001976.1	0.59	Terpene	eupenifeldin	Phoma sp.
BGC0001977.1	0.59	Other	eupenifeldin	Phoma sp.
BGC0001144.1	0.59	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000861.1	0.58	Other	eicosapentaenoic acid	Shewanella sp. BR-2

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 20491:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

XBJ1_2946

Search NORINE for peptide: strict or relaxed

AMP-binding (35..212): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: De--Cd---K
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 30% (weak)

XBJ1_2953

PKS_AT (593..896): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 41.5
Methoxymalonyl-CoA: 26.3
Methylmalonyl-CoA: 19.9
Acetyl-CoA: 19.1
fatty_acid: 10.8
Benzoyl-CoA: 9.0
inactive: 8.2
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0