BGC0001892 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001892 (Botrytis cinerea B05.10)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	64,068

BGC0001892 - Region 1 - T1PKS

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Location: 1 - 64,068 nt. (total: 64,068 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 64,069
Label		BGC0001892

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001892.1	1.12	Polyketide	botcinic acid	Botrytis cinerea B05.10
BGC0001068.1	0.56	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001858.1	0.47	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001909.1	0.46	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000003.1	0.44	Polyketide	AF-toxin	Alternaria alternata
BGC0001775.1	0.44	Terpene	sespendole	Cordana terrestris
BGC0000631.1	0.43	Terpene	botrydial	Botrytis cinerea B05.10
BGC0001280.1	0.42	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.42	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000688.1	0.42	Terpene	copalyl diphosphate	Diaporthe amygdali

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001892.1	0.98	Polyketide	botcinic acid	Botrytis cinerea B05.10
BGC0001068.1	0.62	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001969.1	0.61	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0000003.1	0.58	Polyketide	AF-toxin	Alternaria alternata
BGC0001277.1	0.58	Terpene	nivalenol, vomitoxin, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, neosolaniol, calonectrin, apotrichodiol, isotrichotriol, 15-deacetylcalonectrin, T-2 toxin, 3-acetyl T-2 toxin, trichodiene	Fusarium graminearum
BGC0000688.1	0.57	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000811.1	0.57	Alkaloid	fumigaclavine C	Aspergillus fumigatus Af293
BGC0001811.1	0.57	Terpene	trichodiene-11-one	Fusarium asiaticum
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000930.1	0.56	Other	deoxynivalenol	Fusarium graminearum

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 64068:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (Me-pk) + (pk)
Non-colinear ordering:: BCIN_01g00060 + BCIN_01g00090

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 35746:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 19721 - 64068:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

BCIN_01g00060

PKS_AT (548..862): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 71.2
Methoxymalonyl-CoA: 60.5
Malonyl-CoA: 54.3
Isobutyryl-CoA: 43.9
Ethylmalonyl-CoA: 42.4
Propionyl-CoA: 35.3
trans-1,2-CPDA: 25.3
CHC-CoA: 18.4
inactive: 17.7
Benzoyl-CoA: 17.4
fatty_acid: 16.0
3-Methylbutyryl-CoA: 14.2
Acetyl-CoA: 11.5
2-Methylbutyryl-CoA: 11.4

BCIN_01g00090

PKS_AT (555..870): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; 2-Methylbutyryl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 75.0
Methoxymalonyl-CoA: 67.4
Ethylmalonyl-CoA: 48.2
Malonyl-CoA: 45.5
Propionyl-CoA: 42.5
fatty_acid: 33.1
trans-1,2-CPDA: 27.1
CHC-CoA: 23.2
2-Methylbutyryl-CoA: 22.3
Benzoyl-CoA: 17.5
Isobutyryl-CoA: 11.2
Acetyl-CoA: 9.1
3-Methylbutyryl-CoA: 5.8
inactive: 0.0