BGC0001913 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001913 (fungal sp. ATCC 74256)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	43,800	cornexistin	Polyketide:Iterative type I	19%

BGC0001913 - Region 1 - T1PKS

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Location: 1 - 43,800 nt. (total: 43,800 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 43,801
Label		BGC0001913

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001913.1	0.67	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0000046.1	0.32	Polyketide	depudecin	Alternaria brassicicola
BGC0001858.1	0.24	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.23	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001124.1	0.21	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001252.1	0.21	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0001446.1	0.21	Polyketide	asparasone A	Aspergillus flavus NRRL3357
BGC0001906.1	0.21	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001284.1	0.21	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0000107.1	0.21	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001913.1	0.87	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0000046.1	0.65	Polyketide	depudecin	Alternaria brassicicola
BGC0001858.1	0.57	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.56	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001124.1	0.54	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001252.1	0.54	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0001446.1	0.53	Polyketide	asparasone A	Aspergillus flavus NRRL3357
BGC0001906.1	0.53	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001284.1	0.53	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0000107.1	0.53	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 35751:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

phiA

PKS_AT (591..913): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 71.2
Methoxymalonyl-CoA: 66.8
Malonyl-CoA: 63.1
Isobutyryl-CoA: 49.3
Propionyl-CoA: 23.9
inactive: 15.3
Benzoyl-CoA: 13.5
CHC-CoA: 12.7
fatty_acid: 10.0
trans-1,2-CPDA: 8.2
2-Methylbutyryl-CoA: 5.8
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -1.8