BGC0001954 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001954 (Talaromyces wortmannii)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	19,896

BGC0001954 - Region 1 - T1PKS

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Location: 1 - 19,896 nt. (total: 19,896 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 19,897
Label		BGC0001954

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001954.1	0.67	NRP, Polyketide	wortmanamide A, wortmanamide B	Talaromyces wortmannii
BGC0000046.1	0.31	Polyketide	depudecin	Alternaria brassicicola
BGC0001068.1	0.29	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000676.1	0.23	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0001254.1	0.22	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001124.1	0.21	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0000107.1	0.21	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0000030.1	0.21	Polyketide	bikaverin	Fusarium fujikuroi IMI 58289
BGC0001265.1	0.21	Polyketide	melanin	Bipolaris oryzae
BGC0000688.1	0.20	Terpene	copalyl diphosphate	Diaporthe amygdali

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001954.1	0.87	NRP, Polyketide	wortmanamide A, wortmanamide B	Talaromyces wortmannii
BGC0000046.1	0.64	Polyketide	depudecin	Alternaria brassicicola
BGC0001068.1	0.62	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000676.1	0.56	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0001254.1	0.55	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001124.1	0.53	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0000107.1	0.53	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0000030.1	0.53	Polyketide	bikaverin	Fusarium fujikuroi IMI 58289
BGC0001265.1	0.53	Polyketide	melanin	Bipolaris oryzae
BGC0000688.1	0.53	Terpene	copalyl diphosphate	Diaporthe amygdali

Similar known gene clusters

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 19896:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

QBC19710.1

PKS_AT (548..859): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 82.9
Methoxymalonyl-CoA: 74.5
Ethylmalonyl-CoA: 55.9
Isobutyryl-CoA: 44.5
Malonyl-CoA: 31.0
Benzoyl-CoA: 28.7
Propionyl-CoA: 26.0
trans-1,2-CPDA: 24.0
fatty_acid: 20.0
3-Methylbutyryl-CoA: 15.6
2-Methylbutyryl-CoA: 15.1
CHC-CoA: 11.4
Acetyl-CoA: 7.5
inactive: 0.0