BGC0002185 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002185 (Penicillium sp)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	28,322	fujikurin A / fujikurin B / fujikurin C / fujikurin D	Polyketide	83%

BGC0002185 - Region 1 - T1PKS

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Location: 1 - 28,322 nt. (total: 28,322 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 28,323
Label		BGC0002185

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001068.1	0.29	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001858.1	0.28	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000676.1	0.25	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0000003.1	0.24	Polyketide	AF-toxin	Alternaria alternata
BGC0001909.1	0.23	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000688.1	0.23	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000046.1	0.21	Polyketide	depudecin	Alternaria brassicicola
BGC0001969.1	0.20	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0001254.1	0.20	Polyketide	ACT-Toxin II	Alternaria alternata

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001068.1	0.62	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001858.1	0.62	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000676.1	0.59	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0000003.1	0.57	Polyketide	AF-toxin	Alternaria alternata
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000688.1	0.56	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000046.1	0.54	Polyketide	depudecin	Alternaria brassicicola
BGC0001969.1	0.53	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0001254.1	0.52	Polyketide	ACT-Toxin II	Alternaria alternata

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 28322:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

grgA

PKS_AT (558..878): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 94.9
Methoxymalonyl-CoA: 69.7
Ethylmalonyl-CoA: 66.3
Isobutyryl-CoA: 52.1
Benzoyl-CoA: 38.7
Propionyl-CoA: 36.3
trans-1,2-CPDA: 26.3
2-Methylbutyryl-CoA: 23.2
fatty_acid: 22.3
Malonyl-CoA: 22.1
CHC-CoA: 19.8
Acetyl-CoA: 18.7
3-Methylbutyryl-CoA: 18.1
inactive: 15.9