BGC0000160 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000160 (Aspergillus terreus NIH2624)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	27,093	patulin	Polyketide:Iterative type I	26%

BGC0000160 - Region 1 - T1PKS

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Location: 1 - 27,093 nt. (total: 27,093 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 27,094
Label		BGC0000160

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000160.1	1.00	Polyketide	terreic acid	Aspergillus terreus NIH2624
BGC0001276.1	0.69	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.1	0.36	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244.1	0.36	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001273.1	0.35	Polyketide	asperlactone	Aspergillus ochraceus
BGC0000046.1	0.32	Polyketide	depudecin	Alternaria brassicicola
BGC0001858.1	0.31	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.28	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000688.1	0.25	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000676.1	0.24	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000160.1	1.00	Polyketide	terreic acid	Aspergillus terreus NIH2624
BGC0001276.1	0.89	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.1	0.69	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244.1	0.68	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001273.1	0.68	Polyketide	asperlactone	Aspergillus ochraceus
BGC0000046.1	0.66	Polyketide	depudecin	Alternaria brassicicola
BGC0001858.1	0.64	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.61	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000688.1	0.59	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000676.1	0.57	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27093:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATEG_06275

PKS_AT (582..873): pk

ATSignature: Malonyl-CoA, Acetyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Acetyl-CoA: 66.7%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 110.4
Ethylmalonyl-CoA: 89.6
Methoxymalonyl-CoA: 84.4
Isobutyryl-CoA: 74.8
Malonyl-CoA: 74.5
Acetyl-CoA: 72.5
2-Methylbutyryl-CoA: 57.9
Propionyl-CoA: 52.9
trans-1,2-CPDA: 40.9
Benzoyl-CoA: 37.2
fatty_acid: 35.4
3-Methylbutyryl-CoA: 32.9
CHC-CoA: 31.6
inactive: 12.6