BGC0000214 - 1 region(s) - antiSMASH results

BGC0000214 (Streptomyces olindensis)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	14,080	cosmomycin D	Saccharide + Polyketide	37%

BGC0000214 - Region 1 - T2PKS

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Location: 1 - 14,080 nt. (total: 14,080 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000214.1	1.00	Polyketide	cosmomycin B	Streptomyces olindensis
BGC0001074.1	0.43	Saccharide, Polyketide	cosmomycin D	Streptomyces olindensis
BGC0001558.1	0.33	Polyketide	cosmomycin C	Streptomyces sp. CNT302
BGC0001568.1	0.33	Polyketide	cytorhodin	Streptomyces sp. SCSIO 1666
BGC0000217.1	0.31	Polyketide	daunorubicin	Streptomyces sp.
BGC0000248.1	0.30	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000218.1	0.30	Polyketide	doxorubicin	Streptomyces peucetius
BGC0000813.1	0.29	Alkaloid	K-252a	Nonomuraea longicatena
BGC0000231.1	0.25	Polyketide	griseusin	Streptomyces griseus
BGC0000056.1	0.24	Polyketide	esperamicin	Actinomadura verrucosospora

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000214.1	1.00	Polyketide	cosmomycin B	Streptomyces olindensis
BGC0001074.1	0.74	Saccharide, Polyketide	cosmomycin D	Streptomyces olindensis
BGC0001558.1	0.66	Polyketide	cosmomycin C	Streptomyces sp. CNT302
BGC0001568.1	0.66	Polyketide	cytorhodin	Streptomyces sp. SCSIO 1666
BGC0000217.1	0.65	Polyketide	daunorubicin	Streptomyces sp.
BGC0000248.1	0.64	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000218.1	0.63	Polyketide	doxorubicin	Streptomyces peucetius
BGC0000813.1	0.63	Alkaloid	K-252a	Nonomuraea longicatena
BGC0000231.1	0.59	Polyketide	griseusin	Streptomyces griseus
BGC0000056.1	0.58	Polyketide	esperamicin	Actinomadura verrucosospora

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 14080
Starter unit(s):: propionyl-CoA (Score: 1347.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 651.5; E-value: 9.7e-199)
Product class(es):: angucycline
anthracycline
aureolic acid
tetracenomycin
tetracycline
Product molecular weight(s):: propionyl-CoA_8: 753.68 Da
propionyl-CoA_9: 795.71 Da

cosB: KS (Score: 747.6; E-value: 7.8e-228)
cosC: CLF 8|9 (Score: 651.5; E-value: 9.7e-199)
cosE: KSIII (Score: 536.2; E-value: 7.2e-164); KSIII ABC00733.1_Cosmomycin_propionyl-CoA (Score: 685.0; E-value: 0.0)
cosF: AT (Score: 447.0; E-value: 9.3e-137); AT ABC00730.1_Cosmomycin_propionyl-CoA (Score: 662.0; E-value: 0.0)
cosG: GT (Score: 467.9; E-value: 8e-143)
cosk: GT (Score: 446.9; E-value: 1.9e-136)