BGC0000348 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000348 (Epichloe festucae var. lolii)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	19,379	dihydrolysergic acid	Alkaloid	50%

BGC0000348 - Region 1 - NRPS

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Location: 1 - 19,379 nt. (total: 19,379 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 19,380
Label		BGC0000348

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000348.1	1.00	NRP	ergovaline	Epichloe festucae var. lolii
BGC0000900.1	0.33	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.33	NRP	dimethylcoprogen	Alternaria alternata
BGC0000427.1	0.31	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.28	NRP	indigoidine	Streptomyces chromofuscus
BGC0001479.1	0.26	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001261.1	0.25	NRP	AM-toxin	Alternaria alternata
BGC0000357.1	0.25	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0001517.1	0.24	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0000979.1	0.24	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000348.1	1.00	NRP	ergovaline	Epichloe festucae var. lolii
BGC0000900.1	0.67	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.67	NRP	dimethylcoprogen	Alternaria alternata
BGC0000427.1	0.64	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.61	NRP	indigoidine	Streptomyces chromofuscus
BGC0001479.1	0.59	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001261.1	0.58	NRP	AM-toxin	Alternaria alternata
BGC0000357.1	0.58	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0001517.1	0.57	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0000979.1	0.57	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 19379:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

lpsB

Search NORINE for peptide: strict or relaxed

AMP-binding (287..684): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvfsvglimk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)