BGC0000275 - 1 region(s) - antiSMASH results

BGC0000275 (Streptomyces glaucescens)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	13,123	elloramycin	Polyketide:Type II + Saccharide:Hybrid/tailoring	36%

BGC0000275 - Region 1 - T2PKS

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Location: 1 - 13,123 nt. (total: 13,123 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000275.1	1.00	Polyketide	tetracenomycin C	Streptomyces glaucescens
BGC0000248.1	0.42	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000231.1	0.32	Polyketide	griseusin	Streptomyces griseus
BGC0000215.1	0.31	Polyketide	curamycin	Streptomyces cyaneus
BGC0000228.1	0.29	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000234.1	0.27	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001513.1	0.27	Polyketide	anthrabenzoxocinone	Actinobacteria bacterium
BGC0000204.1	0.24	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0001366.1	0.23	Polyketide	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2
BGC0001197.1	0.23	Polyketide	frankiamicin	Frankia sp. EAN1pec

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000275.1	1.00	Polyketide	tetracenomycin C	Streptomyces glaucescens
BGC0000248.1	0.74	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000231.1	0.66	Polyketide	griseusin	Streptomyces griseus
BGC0000215.1	0.65	Polyketide	curamycin	Streptomyces cyaneus
BGC0000228.1	0.62	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000234.1	0.60	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001513.1	0.60	Polyketide	anthrabenzoxocinone	Actinobacteria bacterium
BGC0000204.1	0.57	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0001366.1	0.57	Polyketide	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2
BGC0001197.1	0.56	Polyketide	frankiamicin	Frankia sp. EAN1pec

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 13123
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 657.9; E-value: 1.1e-200)
Product class(es):: tetracenomycin
Product molecular weight(s):: acetyl-CoA_8: 376.44 Da
acetyl-CoA_9: 418.48 Da

tcmG: OXY (Score: 312.0; E-value: 1.8e-95)
tcmI: CYC C4-C21/C2-C23|C2-C19 (Score: 161.0; E-value: 1.7e-50)
tcmJ: CYC C5-C18 (Score: 203.5; E-value: 2.2e-63)
tcmK: KS (Score: 759.2; E-value: 2.4e-231)
tcmL: CLF 8|9 (Score: 657.9; E-value: 1.1e-200)
tcmM: ACP (Score: 89.8; E-value: 2e-28)
tcmN: CYC C9-C14 (Score: 240.4; E-value: 1.4e-74); MET C11O (Score: 546.0; E-value: 6.7e-167)
tcmO: MET C13O|C17O (Score: 433.2; E-value: 1.3e-132)
tcmP: MET carboxy_O (Score: 277.5; E-value: 1.9e-85)