BGC0002234 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002234 (Aspergillus ruber CBS 135680)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS,indole	1	20,938	epipyriculol	Polyketide	17%

BGC0002234 - Region 1 - T1PKS,indole

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Location: 1 - 20,938 nt. (total: 20,938 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
indole: (indsynth or dmat or indole_PTase)

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 20,939
Label		BGC0002234

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001241.1	0.64	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.64	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001375.1	0.45	Terpene	penitrem A, penitrem B, penitrem C, penitrem D, penitrem E, penitrem F	Penicillium simplicissimum
BGC0000286.1	0.41	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0002076.1	0.39	Other	4,5-Dehydroacaterin, Acaterin	Pseudomonas jessenii
BGC0001858.1	0.38	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000671.1	0.37	Terpene	momilactone	Oryza sativa Japonica Group
BGC0001936.1	0.34	Terpene	nodulisporic acid F	Hypoxylon pulicicidum
BGC0001706.1	0.34	Terpene	nodulisporic acid F	Hypoxylon pulicicidum
BGC0000234.1	0.33	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001241.1	0.65	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.65	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001280.1	0.64	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.64	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001068.1	0.62	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000046.1	0.58	Polyketide	depudecin	Alternaria brassicicola
BGC0001892.1	0.57	Polyketide	botcinic acid	Botrytis cinerea B05.10
BGC0001141.1	0.57	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0000003.1	0.57	Polyketide	AF-toxin	Alternaria alternata
BGC0002076.1	0.57	Other	4,5-Dehydroacaterin, Acaterin	Pseudomonas jessenii

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 20938:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

EURHEDRAFT_499888

PKS_AT (537..856): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 61.5
Methoxymalonyl-CoA: 54.8
Malonyl-CoA: 35.4
Propionyl-CoA: 31.8
Isobutyryl-CoA: 22.4
trans-1,2-CPDA: 21.1
fatty_acid: 20.1
Ethylmalonyl-CoA: 19.9
CHC-CoA: 16.5
Acetyl-CoA: 13.7
inactive: 10.8
Benzoyl-CoA: 10.7
2-Methylbutyryl-CoA: 10.1
3-Methylbutyryl-CoA: 0.0