BGC0000192 - 1 region(s) - antiSMASH results

BGC0000192 (Streptomyces galilaeus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	PKS-like,T2PKS	1	15,155	aclacinomycin	Polyketide	60%

BGC0000192 - Region 1 - PKS-like,T2PKS

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Location: 1 - 15,155 nt. (total: 15,155 nt) Show pHMM detection rules used

Region on contig edge.

PKS-like: (t2pks2 or ksIII)
T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000192.1	2.00	Polyketide	aclacinomycin	Streptomyces galilaeus
BGC0000191.1	1.13	Polyketide	aclacinomycin	Streptomyces galilaeus
BGC0000217.1	0.92	Polyketide	daunorubicin	Streptomyces sp.
BGC0000231.1	0.89	Polyketide	griseusin	Streptomyces griseus
BGC0000218.1	0.87	Polyketide	doxorubicin	Streptomyces peucetius
BGC0000248.1	0.85	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000212.1	0.70	Polyketide	cinerubin B	Streptomyces sp. SPB074
BGC0000234.1	0.66	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723.1	0.60	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000272.1	0.55	Polyketide	spore pigment	Streptomyces collinus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000192.1	1.00	Polyketide	aclacinomycin	Streptomyces galilaeus
BGC0000191.1	0.82	Polyketide	aclacinomycin	Streptomyces galilaeus
BGC0000217.1	0.76	Polyketide	daunorubicin	Streptomyces sp.
BGC0000231.1	0.75	Polyketide	griseusin	Streptomyces griseus
BGC0000218.1	0.74	Polyketide	doxorubicin	Streptomyces peucetius
BGC0000248.1	0.74	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000212.1	0.68	Polyketide	cinerubin B	Streptomyces sp. SPB074
BGC0000234.1	0.66	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723.1	0.64	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000272.1	0.61	Polyketide	spore pigment	Streptomyces collinus

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 15155
Starter unit(s):: propionyl-CoA (Score: 1396.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 676.9; E-value: 1.9e-206)
Product class(es):: anthracycline
Product molecular weight(s):: propionyl-CoA_8: 558.57 Da
propionyl-CoA_9: 600.61 Da

aknA: KR C9 (Score: 484.8; E-value: 1.3e-148)
aknB: KS (Score: 725.2; E-value: 4.9e-221)
aknC: CLF 8|9 (Score: 676.9; E-value: 1.9e-206)
aknD: ACP (Score: 108.3; E-value: 3.4e-34)
aknE1: CYC C7-C12 (Score: 517.7; E-value: 1.9e-158)
aknE2: KSIII (Score: 528.4; E-value: 1.8e-161); KSIII AAF70109.1_Aclacinomycin_propionyl-CoA (Score: 729.0; E-value: 0.0)
aknF: AT (Score: 480.8; E-value: 5e-147); AT AAF70110.1_Aclacinomycin_propionyl-CoA (Score: 667.0; E-value: 0.0)
aknG: MET carboxy_O (Score: 431.2; E-value: 2.7e-132)
aknH: CYC C2-C19 (Score: 289.9; E-value: 5.9e-90)
aknK: GT (Score: 513.1; E-value: 1.4e-156)