BGC0000269 - 1 region(s) - antiSMASH results

BGC0000269 (Streptomyces sp. SF2575)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS,PKS-like	1	53,273	polyketomycin	Polyketide:Iterative type I + Polyketide:Type II + Saccharide:Hybrid/tailoring	30%

BGC0000269 - Region 1 - PKS-like,T2PKS

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Location: 1 - 53,273 nt. (total: 53,273 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)
PKS-like: (t2pks2 or ksIII)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000269.1	1.64	Polyketide, Saccharide	SF2575	Streptomyces sp. SF2575
BGC0000248.1	0.86	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000272.1	0.83	Polyketide	spore pigment	Streptomyces collinus
BGC0000885.1	0.68	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000231.1	0.64	Polyketide	griseusin	Streptomyces griseus
BGC0000846.1	0.56	Other	tabtoxin	Pseudomonas syringae
BGC0001458.1	0.56	Other, , (, A, m, i, n, o, c, o, u, m, a, r, i, n, )	salinipostin G	Salinispora tropica CNB-440
BGC0000228.1	0.55	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000841.1	0.53	Other, , (, N, o, n, -, N, R, P, , b, e, t, a, -, l, a, c, t, a, m, )	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0000937.1	0.52	Other	fosfazinomycin A	Streptomyces sp. WM6372

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000269.1	1.00	Polyketide, Saccharide	SF2575	Streptomyces sp. SF2575
BGC0000272.1	0.73	Polyketide	spore pigment	Streptomyces collinus
BGC0000231.1	0.69	Polyketide	griseusin	Streptomyces griseus
BGC0000248.1	0.69	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000885.1	0.67	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000846.1	0.62	Other	tabtoxin	Pseudomonas syringae
BGC0001458.1	0.62	Other, , (, A, m, i, n, o, c, o, u, m, a, r, i, n, )	salinipostin G	Salinispora tropica CNB-440
BGC0000234.1	0.60	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000888.1	0.60	Other	bacilysin	Bacillus sp. CS93
BGC0000841.1	0.60	Other, , (, N, o, n, -, N, R, P, , b, e, t, a, -, l, a, c, t, a, m, )	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 9930 to 53273
Starter unit(s):: malonamyl-CoA (Score: 2319.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 661.0; E-value: 1.3e-201)
Product class(es):: angucycline
anthracycline
aureolic acid
tetracenomycin
tetracycline
Product molecular weight(s):: malonamyl-CoA_8: 654.63 Da
malonamyl-CoA_9: 696.67 Da

ssfA: KS (Score: 751.9; E-value: 3.9e-229)
ssfB: CLF 8|9 (Score: 661.0; E-value: 1.3e-201)
ssfC: ACP (Score: 122.0; E-value: 1.7e-38)
ssfD: AMID (Score: 1218.5; E-value: 0.0); AMID ADE34521.1_SF2575_malonamyl-CoA (Score: 1250.0; E-value: 0.0)
ssfF: KR (Score: 135.5; E-value: 6.1e-42)
ssfK: KR (Score: 181.3; E-value: 6.5e-56)
ssfL2: LIG (Score: 787.9; E-value: 8.6e-240); LIG ADE34493.1_SF2575_malonamyl-CoA (Score: 1069.0; E-value: 0.0)
ssfM1: MET C2O|C2N (Score: 412.1; E-value: 3.7e-126)
ssfM2: MET (Score: 260.4; E-value: 5.4e-80)
ssfO1: OXY (Score: 492.4; E-value: 3.6e-150)
ssfS6: GT (Score: 397.9; E-value: 1.4e-121)
ssfU: KR C9 (Score: 464.8; E-value: 1.7e-142)