BGC0001699 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001699 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	30,427	cyclo-(D-Phe-L-Phe-D-Val-L-Val) / cyclo-(D-Tyr-L-Phe-D-Val-L-Val) / cyclo-(D-Tyr-L-Trp-D-Val-L-Val) / cyclo-(D-Phe-L-Trp-D-Val-L-Val) / cyclo-(D-Phe-L-Phe-D-Val-L-Ile) / cyclo-(D-Phe-L-Phe-D-Ile-L-Val) / cyclo-(D-Tyr-L-Trp-D-Val-L-Ile) / cyclo-(D-Tyr-L-Trp-D-Ile-L-Val) / cyclo-(D-Tyr-L-Phe-D-Val-L-Ile) / cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	NRP:Cyclic depsipeptide	100%

BGC0001699 - Region 1 - NRPS

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Location: 1 - 30,427 nt. (total: 30,427 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 30,428
Label		BGC0001699

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001699.1	0.89	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001517.1	0.24	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0000357.1	0.24	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0001166.1	0.23	NRP	HC-toxin	Alternaria jesenskae
BGC0001220.1	0.21	NRP	aculeacin A	Aspergillus japonicus
BGC0001240.1	0.20	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001132.1	0.20	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.20	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001996.1	0.16	Other	oryzine A, oryzine B	Aspergillus oryzae RIB40
BGC0000410.1	0.16	NRP	pseudomonine	Pseudomonas fluorescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001699.1	0.96	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001517.1	0.57	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0000357.1	0.57	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0001166.1	0.56	NRP	HC-toxin	Alternaria jesenskae
BGC0001220.1	0.54	NRP	aculeacin A	Aspergillus japonicus
BGC0001240.1	0.53	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001132.1	0.52	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.52	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001996.1	0.47	Other	oryzine A, oryzine B	Aspergillus oryzae RIB40
BGC0000410.1	0.47	NRP	pseudomonine	Pseudomonas fluorescens

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 30427:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ANIA_01242

Search NORINE for peptide: strict or relaxed

AMP-binding (250..618): X

NRPSPredictor2: hydrophobic-aromatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---clvgvck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1756..2148): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmqcvffstk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2756..3157): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvlsfgaiik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3814..4213): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dalftggvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)