BGC0001442 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001442 (Streptomyces sp)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	32,297	actinonin	Polyketide	100%

BGC0001442 - Region 1 - NRPS

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Location: 1 - 32,297 nt. (total: 32,297 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 32,298
Label		BGC0001442

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001442.1	0.97	NRP	actinonin	Streptomyces sp. strain ATCC 14903
BGC0001497.1	0.97	Polyketide	actinonin	Streptomyces sp.
BGC0001399.1	0.32	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000885.1	0.32	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001637.1	0.29	NRP	kleboxymycin	Klebsiella oxytoca
BGC0000846.1	0.28	Other	tabtoxin	Pseudomonas syringae
BGC0002071.1	0.28	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001627.1	0.27	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0000465.1	0.27	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.26	NRP	sevadicin	Paenibacillus larvae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001442.1	0.99	NRP	actinonin	Streptomyces sp. strain ATCC 14903
BGC0001497.1	0.99	Polyketide	actinonin	Streptomyces sp.
BGC0001399.1	0.66	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000885.1	0.65	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001637.1	0.63	NRP	kleboxymycin	Klebsiella oxytoca
BGC0000846.1	0.61	Other	tabtoxin	Pseudomonas syringae
BGC0002071.1	0.61	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001627.1	0.61	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0000465.1	0.60	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.60	NRP	sevadicin	Paenibacillus larvae

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 32297:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

actE

Search NORINE for peptide: strict or relaxed

AMP-binding (567..968): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFvAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 90% (moderate)

actH

Search NORINE for peptide: strict or relaxed

AMP-binding (10..412): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVfK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 90% (moderate)