BGC0001469 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001469 (Brevibacillus sp. Leaf182)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	30,053

BGC0001469 - Region 1 - NRPS

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Location: 1 - 30,053 nt. (total: 30,053 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 30,054
Label		BGC0001469

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001469.1	0.79	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0000389.1	0.33	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.33	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0000396.1	0.27	NRP	nodularin	Nostoc sp. 73.1
BGC0001873.1	0.26	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000342.1	0.26	NRP	enniatin	Fusarium equiseti
BGC0000457.1	0.25	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.24	NRP	xenematide	Xenorhabdus nematophila AN6/1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001469.1	0.92	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0000389.1	0.66	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.66	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0000396.1	0.60	NRP	nodularin	Nostoc sp. 73.1
BGC0001873.1	0.59	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000342.1	0.59	NRP	enniatin	Fusarium equiseti
BGC0000457.1	0.58	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001132.1	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.57	NRP	xenematide	Xenorhabdus nematophila AN6/1

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 30053:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ile) + (D-ser - cys - cys - cys - cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ASG16_028340

Search NORINE for peptide: strict or relaxed

AMP-binding (469..873): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVfHFSLIhK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 80% (moderate)

AMP-binding (1987..2369): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (3024..3406): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (4061..4443): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (5101..5497): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ASG16_028345

Search NORINE for peptide: strict or relaxed

AMP-binding (472..878): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DGFFLGVVYK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)