BGC0002017 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002017 (Nocardiopsis potens DSM 45234)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	12,514	fuscachelin A / fuscachelin B / fuscachelin C	NRP	55%

BGC0002017 - Region 1 - NRPS

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Location: 1 - 12,514 nt. (total: 12,514 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 12,515
Label		BGC0002017

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000359.1	0.28	NRP	fuscachelin A, fuscachelin B, fuscachelin C	Thermobifida fusca YX
BGC0001261.1	0.28	NRP	AM-toxin	Alternaria alternata
BGC0001132.1	0.27	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.27	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.26	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000342.1	0.26	NRP	enniatin	Fusarium equiseti
BGC0001128.1	0.26	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.1	0.26	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000313.1	0.26	NRP	beauvericin	Beauveria bassiana
BGC0001844.1	0.26	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000359.1	0.62	NRP	fuscachelin A, fuscachelin B, fuscachelin C	Thermobifida fusca YX
BGC0001261.1	0.62	NRP	AM-toxin	Alternaria alternata
BGC0001132.1	0.61	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.60	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.60	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000342.1	0.59	NRP	enniatin	Fusarium equiseti
BGC0001128.1	0.59	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.1	0.59	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000313.1	0.59	NRP	beauvericin	Beauveria bassiana
BGC0001844.1	0.59	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 12514:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg4_1

Search NORINE for peptide: strict or relaxed

AMP-binding (3..385): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PMPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg4_5

Search NORINE for peptide: strict or relaxed

AMP-binding (479..876): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1543..1938): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)