BGC0002437 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002437 (Thermoactinomyces sp. AS95)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	10,596

BGC0002437 - Region 1 - NRPS

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Location: 1 - 10,596 nt. (total: 10,596 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 10,597
Label		BGC0002437

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001132.1	0.27	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.1	0.27	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001261.1	0.27	NRP	AM-toxin	Alternaria alternata
BGC0001135.1	0.26	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.26	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.26	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000342.1	0.25	NRP	enniatin	Fusarium equiseti
BGC0001844.1	0.25	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001873.1	0.25	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0001758.1	0.24	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001132.1	0.61	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.1	0.61	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001261.1	0.60	NRP	AM-toxin	Alternaria alternata
BGC0001135.1	0.60	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.60	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.60	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000342.1	0.59	NRP	enniatin	Fusarium equiseti
BGC0001844.1	0.59	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001873.1	0.59	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0001758.1	0.58	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 10596:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ile - leu - D-leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

AYX07_11040

Search NORINE for peptide: strict or relaxed

AMP-binding (467..862): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGFFvGgVFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 80% (moderate)

AMP-binding (1505..1886): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (2529..2910): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)