BGC0001650 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001650 (Lysobacter enzymogenes)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	26,129	lysobactin	NRP	2%

BGC0001650 - Region 1 - NRPS

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Location: 1 - 26,129 nt. (total: 26,129 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 26,130
Label		BGC0001650

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001650.1	1.00	NRP	Le-pyrrolopyrazines	Lysobacter enzymogenes
BGC0001434.1	0.38	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.38	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis
BGC0000389.1	0.37	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.36	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001050.1	0.36	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000427.1	0.34	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000438.1	0.33	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0001132.1	0.33	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.33	NRP	sevadicin	Paenibacillus larvae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001650.1	1.00	NRP	Le-pyrrolopyrazines	Lysobacter enzymogenes
BGC0001434.1	0.70	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.70	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis
BGC0000389.1	0.69	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.69	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001050.1	0.69	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000427.1	0.67	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000438.1	0.67	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0001132.1	0.66	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.66	NRP	sevadicin	Paenibacillus larvae

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 26129:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro) + (pro - X) + (phe - pro - bht)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATD51278.1

Search NORINE for peptide: strict or relaxed

AMP-binding (167..575): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALlMGAVcK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

AMP-binding (1238..1661): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQhvAHVaK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 70% (weak)

AMP-binding (2342..2762): bht

NRPSPredictor2: bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAfTLGAvCK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 80% (moderate)

ATD51279.1

Search NORINE for peptide: strict or relaxed

AMP-binding (30..454): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQhIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 90% (moderate)

AMP-binding (1123..1524): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAiyLGVVlK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 70% (weak)

ATD51280.1

Search NORINE for peptide: strict or relaxed

AMP-binding (545..962): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQhAAHVaK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 80% (moderate)