BGC0001752 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001752 (Streptomyces roseifaciens)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	39,092	scabichelin	NRP	40%

BGC0001752 - Region 1 - NRPS

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Location: 1 - 39,092 nt. (total: 39,092 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 39,093
Label		BGC0001752

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001752.1	0.77	NRP	qinichelins	Streptomyces sp. MBT76
BGC0000389.1	0.40	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.39	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0000457.1	0.31	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001135.1	0.31	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001833.1	0.30	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001844.1	0.30	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001131.1	0.30	NRP	ambactin	Xenorhabdus miraniensis
BGC0000396.1	0.30	NRP	nodularin	Nostoc sp. 73.1
BGC0000351.1	0.29	NRP	exochelin	Mycolicibacterium smegmatis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001752.1	0.92	NRP	qinichelins	Streptomyces sp. MBT76
BGC0000389.1	0.72	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.71	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0000457.1	0.64	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001135.1	0.64	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001833.1	0.64	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001844.1	0.63	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001131.1	0.63	NRP	ambactin	Xenorhabdus miraniensis
BGC0000396.1	0.63	NRP	nodularin	Nostoc sp. 73.1
BGC0000351.1	0.63	NRP	exochelin	Mycolicibacterium smegmatis

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 39092:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-ser - X - D-ser) + (ser - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_orf1264

Search NORINE for peptide: strict or relaxed

AMP-binding (475..870): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (2116..2530): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSWdLGfVDK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 80% (moderate)

AMP-binding (3191..3593): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_orf1265

Search NORINE for peptide: strict or relaxed

AMP-binding (504..903): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (1578..1983): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMwNLGLINK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 90% (moderate)

AMP-binding (2644..3053): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMwNLGLINK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 90% (moderate)